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CHEBI:17703 - 26-hydroxycholesterol

ChEBI IDCHEBI:17703
ChEBI Name26-hydroxycholesterol
Stars
DefinitionAn oxysterol that is cholesterol substituted at position 26 by a hydroxy group.
Secondary ChEBI IDsCHEBI:1311, CHEBI:11665, CHEBI:19816
Last Modified14 May 2024
DownloadsMolfile
FormulaC27H46O2
Net Charge0
Average Mass402.663
Monoisotopic Mass402.34978
SMILES[H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@@]1(C)[C@@]2([H])CC[C@]1([H])[C@H](C)CCCC(C)CO
InChIInChI=1S/C27H46O2/c1-18(17-28)6-5-7-19(2)23-10-11-24-22-9-8-20-16-21(29)12-14-26(20,3)25(22)13-15-27(23,24)4/h8,18-19,21-25,28-29H,5-7,9-17H2,1-4H3/t18?,19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
InChIKeyFYHRJWMENCALJY-CCDZVGGQSA-N
Species of MetaboliteComponentSourceComments
Homo sapiens (ncbitaxon:9606) - DOI (10.1038/nbt.2488)
Roles Classification
Biological Roles:
EC 3.1.1.1 (carboxylesterase) inhibitor  Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of carboxylesterase (EC 3.1.1.1 ).
human metabolite  Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
ChEBI Ontology
Outgoing Relation(s)
26-hydroxycholesterol (CHEBI:17703) has functional parent cholesterol (CHEBI:16113)
26-hydroxycholesterol (CHEBI:17703) has role EC 3.1.1.1 (carboxylesterase) inhibitor (CHEBI:78444)
26-hydroxycholesterol (CHEBI:17703) has role human metabolite (CHEBI:77746)
26-hydroxycholesterol (CHEBI:17703) is a 26-hydroxy steroid (CHEBI:36852)
26-hydroxycholesterol (CHEBI:17703) is a 3β-hydroxy-Δ5-steroid (CHEBI:1722)
26-hydroxycholesterol (CHEBI:17703) is a oxysterol (CHEBI:53030)
Incoming Relation(s)
26-hydroxycholesterol 3-sulfate (CHEBI:35419) has functional parent 26-hydroxycholesterol (CHEBI:17703)
(25R)-cholest-5-ene-3β,26-diol (CHEBI:76591) is a 26-hydroxycholesterol (CHEBI:17703)
IUPAC Name 
cholest-5-ene-3β,26-diol
Synonyms  Source
27-HydroxycholesterolKEGG COMPOUND
26-HydroxycholesterolKEGG COMPOUND
Cholest-5-ene-3beta,27-diolKEGG COMPOUND
Cholest-5-ene-3beta,26-diolKEGG COMPOUND
27-HydroxycholesterolKEGG COMPOUND
UniProt Name  Source
26-hydroxycholesterolUniProt
Manual XrefsDatabases
C15610KEGG COMPOUND
LMST01010057LIPID MAPS
Registry NumbersSources
Beilstein:4708620Beilstein
CAS:13095-61-9KEGG COMPOUND
Citations