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CHEBI:101854 - talarozole

ChEBI IDCHEBI:101854
ChEBI Nametalarozole
Stars
DefinitionA racemate comprising equimolar amounts of (R)- and (S)-talarozole. It is used for the treatment of keratinization disorders, psoriasis and acne.
Last Modified1 April 2016
FormulaC21H23N5S
Net Charge0
Average Mass377.508
Monoisotopic Mass377.16742
Wikipedia
Roles Classification
Biological Role:
P450 inhibitor  An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances.
Application:
keratolytic drug  A drug that softens, separates, and causes desquamation of the cornified epithelium or horny layer of skin. Keratolytic drugs are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases.
ChEBI Ontology
Outgoing Relation(s)
talarozole (CHEBI:101854) has part (R)-talarozole (CHEBI:102030)
talarozole (CHEBI:101854) has part (S)-talarozole (CHEBI:102131)
talarozole (CHEBI:101854) has role keratolytic drug (CHEBI:50176)
talarozole (CHEBI:101854) has role P450 inhibitor (CHEBI:50183)
talarozole (CHEBI:101854) is a racemate (CHEBI:60911)
IUPAC Name 
rac-N-{4-[2-ethyl-1-(1H-1,2,4-triazol-1-yl)butyl]phenyl}-1,3-benzothiazol-2-amine
INN  Source
talarozoleKEGG DRUG
Synonyms  Source
R 115866ChemIDplus
N-(4-(2-Ethyl-1-(1H-1,2,4-triazol-1-yl)butyl)phenyl)-2-benzothiazolamineChemIDplus
N-(4-((1RS)-2-Ethyl-1-(1H-1,2,4-triazol-1-yl)butyl)phenyl)benzothiazol-2-amineChemIDplus
R115866ChemIDplus
(RS)-talarozoleChEBI
(±)-talarozoleChEBI
Brand Name  Source
RambazoleKEGG DRUG
Manual XrefsDatabases
D09385KEGG DRUG
TalarozoleWikipedia
Registry NumbersSources
Reaxys:11737106Reaxys
CAS:201410-53-9KEGG DRUG
CAS:201410-53-9ChemIDplus
Citations