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CHEBI:101854 - talarozole
| ChEBI ID | CHEBI:101854 |
| ChEBI Name | talarozole |
| Stars | |
| Definition | A racemate comprising equimolar amounts of (R)- and (S)-talarozole. It is used for the treatment of keratinization disorders, psoriasis and acne. |
| Last Modified | 1 April 2016 |
| Formula | C21H23N5S |
| Net Charge | 0 |
| Average Mass | 377.508 |
| Monoisotopic Mass | 377.16742 |
| Wikipedia |
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| Roles Classification |
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| Biological Role: | P450 inhibitor An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. |
| Applications: | anti-inflammatory agent Any compound that has anti-inflammatory effects. keratolytic drug A drug that softens, separates, and causes desquamation of the cornified epithelium or horny layer of skin. Keratolytic drugs are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases. antipsoriatic A drug used to treat psoriasis. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| talarozole (CHEBI:101854) has part (R)-talarozole (CHEBI:102030) |
| talarozole (CHEBI:101854) has part (S)-talarozole (CHEBI:102131) |
| talarozole (CHEBI:101854) has role anti-inflammatory agent (CHEBI:67079) |
| talarozole (CHEBI:101854) has role antipsoriatic (CHEBI:50748) |
| talarozole (CHEBI:101854) has role keratolytic drug (CHEBI:50176) |
| talarozole (CHEBI:101854) has role P450 inhibitor (CHEBI:50183) |
| talarozole (CHEBI:101854) is a organic molecular entity (CHEBI:50860) |
| talarozole (CHEBI:101854) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac-N-{4-[2-ethyl-1-(1H-1,2,4-triazol-1-yl)butyl]phenyl}-1,3-benzothiazol-2-amine |
| INNs | Source |
|---|---|
| talarozol | WHO MedNet |
| talarozole | KEGG DRUG |
| Synonyms | Source |
|---|---|
| (RS)-talarozole | ChEBI |
| N-(4-((1RS)-2-Ethyl-1-(1H-1,2,4-triazol-1-yl)butyl)phenyl)benzothiazol-2-amine | ChemIDplus |
| N-(4-(2-Ethyl-1-(1H-1,2,4-triazol-1-yl)butyl)phenyl)-2-benzothiazolamine | ChemIDplus |
| R 115866 | ChemIDplus |
| R-115866 | ChEMBL |
| R115866 | ChemIDplus |
| Brand Name | Source |
|---|---|
| Rambazole | KEGG DRUG |
| Manual Xrefs | Databases |
|---|---|
| D09385 | KEGG DRUG |
| Talarozole | Wikipedia |
| Registry Numbers | Sources |
|---|---|
| Reaxys:11737106 | Reaxys |
| CAS:201410-53-9 | KEGG DRUG |
| CAS:201410-53-9 | ChemIDplus |
| Citations |
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