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CHEBI:10124 - zolmitriptan

ChEBI IDCHEBI:10124
ChEBI Namezolmitriptan
Stars
DefinitionA member of the class of tryptamines that is N,N-dimethyltryptamine in which the hydrogen at position 5 of the indole ring has been replaced by a [(4S)-2-oxo-1,3-oxazolidin-4-yl]methyl group. A serotonin 5-HT1 B and D receptor agonist, it is used for the treatment of migraine.
Last Modified3 August 2018
DownloadsMolfile
FormulaC16H21N3O2
Net Charge0
Average Mass287.363
Monoisotopic Mass287.16338
SMILESCN(C)CCc1cnc2ccc(C[C@H]3COC(=O)N3)cc12
InChIInChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1
InChIKeyULSDMUVEXKOYBU-ZDUSSCGKSA-N
Wikipedia
Roles Classification
Biological Role:
serotonergic agonist  An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
Applications:
serotonergic agonist  An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
anti-inflammatory drug  A substance that reduces or suppresses inflammation.
vasoconstrictor agent  Drug used to cause constriction of the blood vessels.
ChEBI Ontology
Outgoing Relation(s)
zolmitriptan (CHEBI:10124) has functional parent N,N-dimethyltryptamine (CHEBI:28969)
zolmitriptan (CHEBI:10124) has role anti-inflammatory drug (CHEBI:35472)
zolmitriptan (CHEBI:10124) has role serotonergic agonist (CHEBI:35941)
zolmitriptan (CHEBI:10124) has role vasoconstrictor agent (CHEBI:50514)
zolmitriptan (CHEBI:10124) is a oxazolidinone (CHEBI:55374)
zolmitriptan (CHEBI:10124) is a tryptamines (CHEBI:27162)
IUPAC Name 
(4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
INNs  Source
zolmitriptanKEGG DRUG
zolmitriptánChEBI
zolmitriptanumChEBI
zolmitriptanChEBI
Synonyms  Source
311C90KEGG COMPOUND
4-[[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-oneIUPHAR
Brand Names  Source
ZomigKEGG DRUG
ZominatDrugCentral
ZomigoroDrugCentral
ZiptonDrugCentral
Manual XrefsDatabases
C07218KEGG COMPOUND
D00415KEGG DRUG
DB00315DrugBank
ZolmitriptanWikipedia
LSM-3208LINCS
2869DrugCentral
Registry NumbersSources
Beilstein:7415010Beilstein
CAS:139264-17-8KEGG COMPOUND
CAS:139264-17-8ChemIDplus