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CHEBI:10110 - zidovudine
| Formula | C10H13N5O4 |
| Net Charge | 0 |
| Average Mass | 267.245 |
| Monoisotopic Mass | 267.09675 |
| SMILES | Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)nc1=O |
| InChI | InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1 |
| InChIKey | HBOMLICNUCNMMY-XLPZGREQSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | HIV-1 reverse transcriptase inhibitor An entity which inhibits the activity of HIV-1 reverse transcriptase. anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. antiviral agent A substance that destroys or inhibits replication of viruses. antimetabolite A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. antiviral drug A substance used in the prophylaxis or therapy of virus diseases. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. antiviral drug A substance used in the prophylaxis or therapy of virus diseases. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| zidovudine (CHEBI:10110) has role anti-HIV agent (CHEBI:64946) |
| zidovudine (CHEBI:10110) has role antifungal agent (CHEBI:35718) |
| zidovudine (CHEBI:10110) has role antiinfective agent (CHEBI:35441) |
| zidovudine (CHEBI:10110) has role antimetabolite (CHEBI:35221) |
| zidovudine (CHEBI:10110) has role antineoplastic agent (CHEBI:35610) |
| zidovudine (CHEBI:10110) has role antitubercular agent (CHEBI:33231) |
| zidovudine (CHEBI:10110) has role antiviral agent (CHEBI:22587) |
| zidovudine (CHEBI:10110) has role antiviral drug (CHEBI:36044) |
| zidovudine (CHEBI:10110) has role HIV-1 reverse transcriptase inhibitor (CHEBI:53756) |
| zidovudine (CHEBI:10110) is a azide (CHEBI:22680) |
| zidovudine (CHEBI:10110) is a pyrimidine 2',3'-dideoxyribonucleoside (CHEBI:48441) |
| IUPAC Name |
|---|
| 3'-azido-3'-deoxythymidine |
| INNs | Source |
|---|---|
| zidovudina | WHO MedNet |
| zidovudine | KEGG DRUG |
| Synonyms | Source |
|---|---|
| 3'-azt | ChEMBL |
| Azidothymidine | ChemIDplus |
| AZT | KEGG COMPOUND |
| Bwa509u | ChEMBL |
| BW A509U | ChEMBL |
| BW-A-509U | ChEMBL |
| Brand Names | Source |
|---|---|
| Retrovir | KEGG DRUG |
| Zidovudine component of combivir | ChEMBL |
| Zidovudine component of lamivudine/ teva | ChEMBL |
| Zidovudine component of trizivir | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| Beilstein:763034 | Beilstein |
| CAS:30516-87-1 | ChemIDplus |
| CAS:30516-87-1 | KEGG COMPOUND |
| CAS:30516-87-1 | DrugBank |
| CAS:30516-87-1 | KEGG DRUG |
| Citations |
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