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CHEBI:10034 - warfarin sodium
| ChEBI ID | CHEBI:10034 |
| ChEBI Name | warfarin sodium |
| Stars | |
| Definition | A racemate comprising equal amounts of (R)- and (S)-warfarin sodium. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice. |
| Last Modified | 28 August 2015 |
| Formula | C19H15NaO4 |
| Net Charge | 0 |
| Average Mass | 330.310 |
| Monoisotopic Mass | 330.08680 |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | vitamin K antagonist A class of anticoagulants which act by inhibiting the action of vitamin K. anti-HBV agent An antiviral agent that destroys or inhibits the replication of the hepatitis B virus. EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor An EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor that interferes with the action of NAD(P)H dehydrogenase (quinone), EC 1.6.5.2. |
| Applications: | antirheumatic drug A drug used to treat rheumatoid arthritis. rodenticide A substance used to destroy rodent pests. anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. anticoagulant An agent that prevents blood clotting. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| warfarin sodium (CHEBI:10034) has part (R)-warfarin sodium (CHEBI:87739) |
| warfarin sodium (CHEBI:10034) has part (S)-warfarin sodium (CHEBI:87740) |
| warfarin sodium (CHEBI:10034) has part warfarin(1−) (CHEBI:50393) |
| warfarin sodium (CHEBI:10034) has role anti-arrhythmia drug (CHEBI:38070) |
| warfarin sodium (CHEBI:10034) has role anti-HBV agent (CHEBI:64951) |
| warfarin sodium (CHEBI:10034) has role anticoagulant (CHEBI:50249) |
| warfarin sodium (CHEBI:10034) has role antirheumatic drug (CHEBI:35842) |
| warfarin sodium (CHEBI:10034) has role cardiovascular drug (CHEBI:35554) |
| warfarin sodium (CHEBI:10034) has role EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor (CHEBI:50390) |
| warfarin sodium (CHEBI:10034) has role rodenticide (CHEBI:33288) |
| warfarin sodium (CHEBI:10034) has role vitamin K antagonist (CHEBI:55347) |
| warfarin sodium (CHEBI:10034) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| sodium 2-oxo-3-(3-oxo-1-phenylbutyl)-2H-benzopyran-4-olate |
| Synonyms | Source |
|---|---|
| 3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin sodium salt | ChemIDplus |
| Aldocumar | ChEMBL |
| Apo-warfarin | ChEMBL |
| rac-warfarin sodium | ChEBI |
| (RS)-warfarin sodium | ChEBI |
| Prothromadin | ChEMBL |
| Brand Names | Source |
|---|---|
| Athrombin | ChEMBL |
| Coumadin | DrugBank |
| Jantoven | DrugBank |
| Marevan | ChEMBL |
| Maveran | DrugBank |
| Panwarfin | ChEMBL |
| Citations |
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