Genome annotation and comparative genomics
The Darwin Tree of Life project aims to sequence the genomes of all 70,000 species of eukaryotic organisms in Britain and Ireland. It is a collaboration between biodiversity, genomics and analysis partners that hopes to transform the way we do biology, conservation and biotechnology.
The Vertebrate Genomes Project (VGP) aims to generate near error-free reference genome assemblies of ~70,000 extant vertebrate species. These genomes will be used to address fundamental questions in biology and disease, to identify species most genetically at risk for extinction, and to preserve genetic information of life.
The Human Pangenome Reference Consortium aims to sequence 300 individuals, producing a pangenome of 600 haplotypes by 2024. The initial phase of the project consists of 47 phased, diploid assemblies from a cohort of genetically diverse individuals.
The European Reference Genome Atlas (ERGA) initiative is a pan-European scientific response to current threats to biodiversity. With approximately one fifth of the ~200,000 European species at risk of extinction, the project aims to form a rapid and coordinated approach to generate high-quality complete genome resources at large scale.
The Quest for Orthologs (QfO) is a joint effort to benchmark, improve and standardize orthology predictions through collaboration, the use of shared reference datasets, and evaluation of emerging new methods.
The AQUA-FAANG project aims to improve understanding the genome function and usage of genotype-to-phenotype prediction in the six most important European farmed fish species.
The regulatory GENomE of SWine and CHicken (GENE-SWitCH) project aims to deliver new underpinning knowledge on the functional genomes of two main monogastric farm species (pig and chicken) and to enable immediate translation to the pig and poultry sectors.