Are you good at predicting protein interactions?

Protein-protein interactions are of fundamental importance to all aspects of biology and medical sciences, and a number of methods have been developed to predict them. CAPRI is a community wide experiment designed to assess predictive methods that are based on structure. If we know the three-dimensional structure of two components of a complex, how reliably can we predict their assembly?

CAPRI, now hosted by EMBL-EBI’s Protein Data Bank in Europe, began in 2001. The experiment has multiple prediction rounds each year, each focussing on one or more protein targets. Significantly, the latest round of CAPRI is being launched collaboratively between CAPRI and CASP, the community experiment for the Critical Assessment of Structure Predictions. With the growing interest in deriving high-resolution information on protein interactions and complexes, the time is ideal to promote a closer collaboration between developers of structure and function prediction methods, and those predicting the association modes of proteins with other macromolecules.

Registration for round 30 of CAPRI is now open. For further information and to register, please visit: http://www.ebi.ac.uk/msd-srv/capri/capri.html