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PDBsum entry 5a8f

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protein Protein-protein interface(s) links
Viral protein PDB id
5a8f

 

 

 

 

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JSmol PyMol  
Contents
Protein chains
219 a.a.
189 a.a.
258 a.a.
PDB id:
5a8f
Name: Viral protein
Title: Structure and genome release mechanism of human cardiovirus saffold virus-3
Structure: Human saffold virus-3 vp1. Chain: a. Genome polyphuman saffold virus-3 vp3 protein. Chain: b. Human saffold virus-3 vp2. Chain: c
Source: Saffold virus. Organism_taxid: 434309. Organism_taxid: 434309
Authors: E.Mullapudi,J.Novacek,L.Palkova,P.Kulich,M.Lindberg, F.J.M.Vankuppeveld,P.Plevka
Key ref: E.Mullapudi et al. (2016). Structure and Genome Release Mechanism of the Human Cardiovirus Saffold Virus 3. J Virol, 90, 7628-7639. PubMed id: 27279624 DOI: 10.1128/JVI.00746-16
Date:
15-Jul-15     Release date:   08-Jun-16    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
C0MHL9  (POLG_SAFV) -  Genome polyprotein from Saffold virus
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
2295 a.a.
219 a.a.*
Protein chain
Pfam   ArchSchema ?
E3TMG9  (E3TMG9_SAFV) -  Genome polyprotein from Saffold virus
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
2295 a.a.
189 a.a.
Protein chain
Pfam   ArchSchema ?
C0MHL9  (POLG_SAFV) -  Genome polyprotein from Saffold virus
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
2295 a.a.
258 a.a.
Key:    PfamA domain  Secondary structure
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class 1: Chains A, C: E.C.2.7.7.48  - RNA-directed Rna polymerase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate
RNA(n)
+ ribonucleoside 5'-triphosphate
= RNA(n+1)
+ diphosphate
   Enzyme class 2: Chains A, C: E.C.3.4.22.28  - picornain 3C.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
   Enzyme class 3: Chains A, B, C: E.C.3.6.4.13  - Rna helicase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + H2O = ADP + phosphate + H+
ATP
+ H2O
= ADP
+ phosphate
+ H(+)
Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

 
    reference    
 
 
DOI no: 10.1128/JVI.00746-16 J Virol 90:7628-7639 (2016)
PubMed id: 27279624  
 
 
Structure and Genome Release Mechanism of the Human Cardiovirus Saffold Virus 3.
E.Mullapudi, J.Nováček, L.Pálková, P.Kulich, A.M.Lindberg, F.J.van Kuppeveld, P.Plevka.
 
  ABSTRACT  
 
No abstract given.

 

 

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