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PDBsum entry 4ogg
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PDB id:
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Lyase
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Title:
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Crystal structure of arabidopsis thaliana dj-1d with glyoxylate as substrate analog
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Structure:
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Protein dj-1 homolog d. Chain: a, b, c. Synonym: atdj1d, lactoylglutathione lyase dj1d. Engineered: yes
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Source:
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Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: dj1d, at3g02720, f13e7.34. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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1.60Å
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R-factor:
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0.185
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R-free:
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0.212
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Authors:
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D.Choi,J.Kim,K.-S.Ryu,C.Park
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Key ref:
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D.Choi
et al.
(2014).
Stereospecific mechanism of DJ-1 glyoxalases inferred from their hemithioacetal-containing crystal structures.
Febs J,
281,
5447-5462.
PubMed id:
DOI:
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Date:
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16-Jan-14
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Release date:
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15-Oct-14
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PROCHECK
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Headers
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References
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Q9M8R4
(DJ1D_ARATH) -
Protein DJ-1 homolog D from Arabidopsis thaliana
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Seq:
Struc:
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388 a.a.
386 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 2 residue positions (black
crosses)
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Enzyme class:
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E.C.4.4.1.5
- lactoylglutathione lyase.
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Reaction:
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(R)-S-lactoylglutathione = methylglyoxal + glutathione
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(R)-S-lactoylglutathione
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=
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methylglyoxal
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+
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glutathione
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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DOI no:
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Febs J
281:5447-5462
(2014)
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PubMed id:
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Stereospecific mechanism of DJ-1 glyoxalases inferred from their hemithioacetal-containing crystal structures.
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D.Choi,
J.Kim,
S.Ha,
K.Kwon,
E.H.Kim,
H.Y.Lee,
K.S.Ryu,
C.Park.
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ABSTRACT
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