PDBsum entry 1ppn

Hydrolase(sulfhydryl proteinase)

PDB id: 1ppn

Contents

Protein chain

212 a.a. *

Ligands

UNL

MOH

Waters ×226

* Residue conservation analysis

PDB id:

1ppn

Name:

Hydrolase(sulfhydryl proteinase)

Title:

Structure of monoclinic papain at 1.60 angstroms resolution

Structure:

Papain. Chain: a. Engineered: yes

Source:

Carica papaya. Papaya. Organism_taxid: 3649

Resolution:

1.60Å R-factor: 0.160

Authors:

R.W.Pickersgill,G.W.Harris,E.Garman

Key ref:

R.W.Pickersgill et al. (1992). Structure of monoclinic papain at 1.60 angstroms resolution. Acta crystallogr ,Sect b, 48, 59.

Date:

25-Oct-91 Release date: 31-Jan-94

Protein chain

P00784  (PAPA1_CARPA) -  Papain from Carica papaya

Seq: 345 a.a.

Struc: 212 a.a.

Enzyme reactions

• Enzyme class: E.C.3.4.22.2 - papain.
• Reaction: Hydrolysis of proteins with broad specificity for peptide bonds, with preference for a residue bearing a large hydrophobic sidechain at the P2 position. Does not accept Val at P1'.