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Ligand clusters for UniProt code Q9UGP5
Ligand clusters for Q9UGP5: DNA polymerase lambda from Homo sapiens
Top 6 (of 22) ligand clusters
Cluster 1.
23 ligand types
105 ligands
Cluster 2.
4 ligand types
6 ligands
Cluster 3.
2 ligand types
2 ligands
Cluster 4.
3 ligand types
4 ligands
Cluster 5.
2 ligand types
3 ligands
Cluster 6.
1 ligand type
1 ligand
Representative protein: 4k4iA
Structures
PDB
Schematic diagram
4k4i
A
5iii
A
5iij
A
2bcv
A
3uq2
A
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Cluster 1 contains 23 ligand types (of which only 20 are listed. Click
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Ligand
Description
_Mg
1. Metal:
_MG × 30
PDB codes:
1xsn
(A),
2bcq
(A),
2bcr
(A),
2bcs
(A),
2bcv
(A),
2pfn
(A),
2pfo
(A),
2pfp
(A),
2pfq
(A),
3c5g
(A),
3hw8
(A),
3hwt
(A),
3hx0
(A),
3mda
(A),
3mdc
(A),
3mgi
(A),
3pml
(A),
3pmn
(A),
3pnc
(A),
3uq2
(A),
4fo6
(A),
4xa5
(A),
4xus
(A),
5ddy
(A),
5iii
(A),
5iij
(A),
5iin
(A).
_Mn
2. Metal:
_MN × 9
PDB codes:
2pfo
(A),
2pfq
(A),
3pmn
(A),
3upq
(A),
4fo6
(A),
5ddy
(A),
3. Ligand:
PPV × 8
pyrophosphoric acid
Pyrophosphate
PDB codes:
1xsp
(A),
2bcq
(A),
2bcr
(A),
2bcs
(A),
2bcu
(A),
2pfq
(A),
3mda
(A),
3uq2
(A).
4. Ligand:
CIT × 3
citric acid
Citric acid
PDB codes:
4x5v
(A),
5iik
(A),
5iil
(A).
5. Ligand:
TRS × 1
tromethamine
2-Amino-2-Hydroxymethyl-Propane-1,3-Diol
PDB code:
3pnc
(A).
_Na
6. Metal:
_NA × 13
PDB codes:
1xsp
(A),
2bcu
(A),
2bcv
(A),
2pfn
(A),
2pfp
(A),
2pfq
(A),
3c5g
(A),
3hw8
(A),
3pnc
(A),
4x5v
(A),
5iik
(A),
5iil
(A),
5iim
(A).
_Ca
7. Metal:
_CA × 8
PDB codes:
4k4g
(A),
4k4h
(A),
4k4i
(A),
5cwr
(A),
8. Ligand:
D3T × 6
2',3'-Dideoxy-Thymidine-5'-Triphosphate
PDB codes:
1xsn
(A),
3c5g
(A),
3hw8
(A),
3hwt
(A),
3hx0
(A),
3mgi
(A).
9. Ligand:
DCP × 5
2'-Deoxycytidine-5'-Triphosphate
PDB codes:
2pfp
(A),
2pfq
(A),
5cwr
(A),
5ddy
(A),
10. Ligand:
DUP × 4
2'-Deoxyuridine 5'-Alpha,Beta-Imido-Triphosphate
PDB codes:
2pfn
(A),
2pfo
(A),
5iim
(A),
5iin
(A).
11. Ligand:
1GC × 3
2'-Deoxy-5'-O-[(R)-Hydroxy{[(s)-Hydroxy(phosphonooxy) phosphoryl]methyl}phosphoryl]guanosine
PDB codes:
3pml
(A),
3pmn
(A),
3pnc
(A).
12. Ligand:
DTP × 2
2'-Deoxyadenosine 5'-Triphosphate
PDB codes:
5dkw
(A),
5iii
(A).
13. Ligand:
SO4 × 2
Sulfate ion
PDB codes:
3uq0
(A),
5cp2
(A).
14. Ligand:
TTP × 2
Thymidine-5'-Triphosphate
PDB codes:
2bcv
(A),
4xus
(A).
15. Ligand:
1RY × 1
[[(2r,5s)-5-(4-Azanyl-5-Fluoranyl-2-Oxidanylidene- Pyrimidin-1-Yl)-1,3-Oxathiolan-2-Yl]methoxy-
Oxidanyl- Phosphoryl] phosphono hydrogen phosphate
PDB code:
4k4i
(A).
16. Ligand:
1RZ × 1
Lamivudine triphosphate
PDB code:
4k4h
(A).
17. Ligand:
1S0 × 1
4-Amino-1-{2-Deoxy-5-O-[(R)-Hydroxy{[(s)- Hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-Beta- L-
Erythro-Pentofuranosyl}pyrimidin-2(1h)-One
PDB code:
4k4g
(A).
18. Ligand:
8DG × 1
8-Oxo-2'-Deoxyguanosine-5'-Triphosphate
PDB code:
4xa5
(A).
19. Ligand:
DCT × 1
2',3'-Dideoxycytidine 5'-Triphosphate
PDB code:
5iij
(A).
20. Ligand:
DOC × 1
2',3'-Dideoxycytidine-5'-Monophosphate
PDB code:
4xus
(A).
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Cluster 2 contains 4 ligand types
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Ligand
Description
1. Ligand:
GOL × 1
glycerin
Glycerol
PDB code:
4xa5
(A).
_Mn
2. Metal:
_MN × 1
PDB code:
3pmn
(A).
3. Ligand:
EDO × 2
1,2-Ethanediol
PDB codes:
2bcq
(A),
2bcr
(A).
4. Ligand:
SO4 × 2
Sulfate ion
PDB codes:
3upq
(A),
3uq0
(A).
Cluster 3 contains 2 ligand types
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Ligand
Description
1. Ligand:
GOL × 1
glycerin
Glycerol
PDB code:
4xa5
(A).
2. Ligand:
EDO × 1
1,2-Ethanediol
PDB code:
2bcr
(A).
Cluster 4 contains 3 ligand types
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Ligand
Description
1. Ligand:
ACT × 2
Acetate ion
PDB codes:
4k4h
(A),
4k4i
(A).
2. Ligand:
EDO × 1
1,2-Ethanediol
PDB code:
2bcr
(A).
_Cl
3. Metal:
_CL × 1
PDB code:
2gws
(A).
Cluster 5 contains 2 ligand types
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Ligand
Description
1. Ligand:
SO4 × 2
Sulfate ion
PDB codes:
3upq
(A),
3uq0
(A).
2. Ligand:
ACT × 1
Acetate ion
PDB code:
4xa5
(A).
Cluster 6 contains 1 ligand type
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Ligand
Description
1. Ligand:
SO4 × 1
Sulfate ion
PDB code:
3upq
(A).