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EBI
Databases
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PDBsum
Ligand clusters for UniProt code O09893
Ligand clusters for O09893: Protease (Fragment) OS=Human immunodeficiency virus 1 GN=pol PE=1 SV=1
1 ligand cluster
Cluster 1.
3 ligand types
3 ligands
Representative protein: 1c6xA
Structures
PDB
Schematic diagram
1c6x
A
1c6z
A
1c6y
A
Cluster 1 contains 3 ligand types
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Ligand
Description
1. Ligand:
MK1 × 1
indinavir
N-[2(r)-Hydroxy-1(s)-Indanyl]-5-[(2(s)-Tertiary butylaminocarbonyl)-4(3-Pyridylmethyl)piperazino]-
4(s)-Hydroxy-2(r)-Phenylmethylpentanamide
PDB code:
1c6y
(A).
2. Ligand:
ROC × 1
saquinavir
(2s)-N-[(2s,3r)-4-[(2s,3s,4as,8as)-3-(Tert- Butylcarbamoyl)-3,4,4a,5,6,7,8,8a-Octahydro-1h-
Isoquinolin-2-Yl]-3-Hydroxy-1-Phenyl-Butan-2-Yl]-2- (Quinolin-2-Ylcarbonylamino)butanediamide
PDB code:
1c6z
(A).
3. Ligand:
3IN × 1
N-[2(s)-Cyclopentyl-1(r)-Hydroxy-3(r)methyl]-5-[(2(s)- Tertiary-Butylamino-Carbonyl)-4-(N1-(2)-(N-
Methylpiperazinyl)-3-Chloro-Pyrazinyl-5-Carbonyl)- Piperazino]-4(s)-Hydroxy-2(r)-Phenylmethyl-
Pentanamide
PDB code:
1c6x
(A).
