PDBsum entry 1tyc

Aminoacyl-tRNA synthase

PDB id: 1tyc

Contents

Protein chain

317 a.a. *

Waters ×171

* Residue conservation analysis

PDB id:

1tyc

Name:

Aminoacyl-tRNA synthase

Title:

Structural analysis of a series of mutants of tyrosyl-tRNA synthetase: enhancement of catalysis by hydrophobic interactions

Structure:

Tyrosyl-tRNA synthetase. Chain: a. Engineered: yes

Source:

Geobacillus stearothermophilus. Organism_taxid: 1422

Biol. unit:

Dimer (from PQS)

Resolution:

2.50Å R-factor: 0.219

Authors:

K.A.Brown,P.Brick,P.De Meester,D.M.Blow

Key ref:

K.A.Brown et al. Structural analysis of a series of mutants of tyrosyl-Trna synthetase: enhancement of catalysis by hydrophobic interactions. To be published, .

Date:

06-Jul-92 Release date: 31-Jan-94

Protein chain

P00952  (SYY_GEOSE) -  Tyrosine--tRNA ligase from Geobacillus stearothermophilus

Seq: 419 a.a.

Struc: 317 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.6.1.1.1 - tyrosine--tRNA ligase.
• Reaction: tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site