_EC 6.1.1.1 Tyrosine--tRNA ligase. 63 PDB entries  
EC 6.-.-.- Ligases. [1,591 PDB entries]
EC 6.1.-.- Forming carbon-oxygen bonds. [549 PDB entries]
EC 6.1.1.- Ligases forming aminoacyl-tRNA and related compounds. [548 PDB entries]
EC 6.1.1.1 Tyrosine--tRNA ligase. [63 PDB entries]    
1h3e

Reaction: Atp + L-tyrosine + tRNA(Tyr) = amp + diphosphate + L-tyrosyl-tRNA(Tyr).
 


ATP
+
L-tyrosine
+
tRNA(Tyr)
=
AMP
+
diphosphate
+
L-tyrosyl-tRNA(Tyr)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): L-tyrosine-tRNA(Tyr) ligase (AMP-forming). Tyrosine translase. Tyrosine tRNA synthetase. Tyrosine-transfer ribonucleate synthetase. Tyrosine-transfer Rna ligase. Tyrosyl-transfer ribonucleate synthetase. Tyrosyl-transfer ribonucleic acid synthetase. Tyrosyl-transfer Rna synthetase. Tyrosyl-tRNA ligase. Tyrosyl-tRNA synthetase.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 63 PDB entries in enzyme class E.C.6.1.1.1

  PDB code Protein
1h3e
Tyrosyl-tRNA synthetase from thermus thermophilus complexed with wild-type trnatyr(gua) and with atp and tyrosinol
Source: Thermus thermophilus. Organism_taxid: 262724. Strain: hb27. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 274
Chain: A (427 residues) CATH domains: 3.40.50.620 1.10.240.10 3.10.290.10
Bound ligands:   Het Group ATP corresponds to enzyme reactant ATP
  Het Group TYE is 92.31% similar to enzyme reactant L-tyrosine
1h3f
Tyrosyl-tRNA synthetase from thermus thermophilus complexed with tyrosinol
Source: Thermus thermophilus. Organism_taxid: 262724. Strain: hb27. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (403 residues) CATH domains: 3.40.50.620 1.10.240.10 3.10.290.10
Bound ligand:   Het Group TYE is 92.31% similar to enzyme reactant L-tyrosine
1j1u
Crystal structure of archaeal tyrosyl-tRNA synthetase complexed with tRNA(tyr) and l-tyrosine
Source: Synthetic: yes. Other_details: this sequence occurs in methanococcus jannaschii.. Methanocaldococcus jannaschii. Organism_taxid: 2190. Gene: tyrs. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (299 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TYR corresponds to enzyme reactant L-tyrosine
1jh3
Solution structure of tyrosyl-tRNA synthetasE C-terminal domain.
Source: Geobacillus stearothermophilus. Organism_taxid: 1422. Gene: tyrs. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (99 residues) CATH domain: 3.10.290.10
1jii
Crystal structure of s. Aureus tyrrs in complex with sb-2193
Source: Staphylococcus aureus. Organism_taxid: 1280. Variant: aureus n315. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (319 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group 383 is 40.00% similar to enzyme reactant L-tyrosine
1jij
Crystal structure of s. Aureus tyrrs in complex with sb-2396
Source: Staphylococcus aureus. Organism_taxid: 1280. Variant: aureus n315. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (319 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group 629 is 40.00% similar to enzyme reactant L-tyrosine
1jik
Crystal structure of s. Aureus tyrrs in complex with sb-2435
Source: Staphylococcus aureus. Organism_taxid: 1280. Variant: aureus n315. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (319 residues) CATH domains: 3.40.50.620 1.10.240.10
1jil
Crystal structure of s. Aureus tyrrs in complex with sb28448
Source: Staphylococcus aureus. Organism_taxid: 1280. Variant: aureus n315. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (323 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group 485 is 42.86% similar to enzyme reactant L-tyrosine
1n3l
Crystal structure of a human aminoacyl-tRNA synthetase cytok
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (332 residues) CATH domains: 3.40.50.620 1.10.240.10
1ntg
Crystal structure of the emap ii-like cytokine released from human tyrosyl-tRNA synthetase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: yars. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (171 residues) CATH domain: 2.40.50.140
1q11
Crystal structure of an active fragment of human tyrosyl-trn synthetase with tyrosinol
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (329 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligands:   Het Group TYE is 92.31% similar to enzyme reactant L-tyrosine
  Het Group PO4 is 55.56% similar to enzyme product diphosphate
1tya
Structural analysis of a series of mutants of tyrosyl-tRNA s enhancement of catalysis by hydrophobic interactions
Source: Geobacillus stearothermophilus. Organism_taxid: 1422
Chain: E (317 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TYR corresponds to enzyme reactant L-tyrosine
1tyb
Structural analysis of a series of mutants of tyrosyl-tRNA s enhancement of catalysis by hydrophobic interactions
Source: Geobacillus stearothermophilus. Organism_taxid: 1422
Chain: E (317 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TYR corresponds to enzyme reactant L-tyrosine
1tyc
Structural analysis of a series of mutants of tyrosyl-tRNA s enhancement of catalysis by hydrophobic interactions
Source: Geobacillus stearothermophilus. Organism_taxid: 1422
Chain: A (317 residues) CATH domains: 3.40.50.620 1.10.240.10
1tyd
Structure of tyrosyl-tRNA synthetase refined at 2.3 angstrom resolution. Interaction of the enzyme with the tyrosyl aden intermediate
Source: Geobacillus stearothermophilus. Organism_taxid: 1422
Chain: E (317 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TYR corresponds to enzyme reactant L-tyrosine
1u7d
Crystal structure of apo m. Jannashii tyrosyl-tRNA synthetase
Source: Methanocaldococcus jannaschii. Organism_taxid: 2190. Gene: tyrs. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (292 residues) CATH domains: 3.40.50.620 1.10.240.10
1u7x
Crystal structure of a mutant m. Jannashii tyrosyl-tRNA synthetase specific for o-methyl-tyrosine
Source: Methanocaldococcus jannaschii. Organism_taxid: 2190. Gene: tyrs. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (306 residues) CATH domains: 3.40.50.620 1.10.240.10
1vbm
Crystal structure of the escherichia coli tyrosyl-tRNA synthetase complexed with tyr-ams
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (318 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group YSA is 48.00% similar to enzyme product AMP
1vbn
Escherichia coli tyrosyl-tRNA synthetase mutant complexed with tyr-ams
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (318 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group YSA is 48.00% similar to enzyme product AMP
1wq3
Escherichia coli tyrosyl-tRNA synthetase mutant comlexed wit l-tyrosine
Source: Escherichia coli str. K12 substr.. Organism_taxid: 316407. Strain: w3110. Gene: tyrs. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (322 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group IYR is 92.86% similar to enzyme reactant L-tyrosine
1wq4
Escherichia coli tyrosyl-tRNA synthetase mutant complexed wi tyrosine
Source: Escherichia coli str. K12 substr.. Organism_taxid: 316407. Strain: w3110. Gene: tyrs. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (321 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TYR corresponds to enzyme reactant L-tyrosine
1x8x
Tyrosyl t-RNA synthetase from e.Coli complexed with tyrosine
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (322 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TYR corresponds to enzyme reactant L-tyrosine
1y42
Crystal structure of a c-terminally truncated cyt-18 protein
Source: Neurospora crassa. Organism_taxid: 5141. Gene: cyt-18. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: X (370 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TYR corresponds to enzyme reactant L-tyrosine
1zh0
Crystal structure of l-3-(2-napthyl)alanine-tRNA synthetase with l-3-(2-napthyl)alanine
Source: Methanocaldococcus jannaschii. Organism_taxid: 2190. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (307 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group NAL is 70.59% similar to enzyme reactant L-tyrosine
1zh6
Crystal structure of p-acetylphenylalanine-tRNA synthetase i with p-acetylphenylalanine
Source: Methanocaldococcus jannaschii. Organism_taxid: 2190. Gene: tyrs. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (307 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group 4AF is 75.00% similar to enzyme reactant L-tyrosine
2ag6
Crystal structure of p-bromo-l-phenylalanine-tRNA sythetase with p-bromo-l-phenylalanine
Source: Methanocaldococcus jannaschii. Organism_taxid: 2190. Gene: tyrs. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (307 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group 4BF is 85.71% similar to enzyme reactant L-tyrosine
2cya
Crystal structure of tyrosyl-tRNA synthetase from aeropyrum
Source: Aeropyrum pernix. Organism_taxid: 56636. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (328 residues) CATH domains: 3.40.50.620 1.10.240.10
2cyb
Crystal structure of tyrosyl-tRNA synthetase complexed with l-tyrosine from archaeoglobus fulgidus
Source: Archaeoglobus fulgidus. Organism_taxid: 2234. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (319 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TYR corresponds to enzyme reactant L-tyrosine
2cyc
Crystal structure of tyrosyl-tRNA synthetase complexed with from pyrococcus horikoshii
Source: Pyrococcus horikoshii. Organism_taxid: 70601. Strain: ot3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (371 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TYR corresponds to enzyme reactant L-tyrosine
2dlc
Crystal structure of the ternary complex of yeast tyrosyl-tr synthetase
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes
Chain: X (339 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group YMP is 61.11% similar to enzyme product AMP
2hgz
Crystal structure of a p-benzoyl-l-phenylalanyl-tRNA synthet
Source: Methanocaldococcus jannaschii. Organism_taxid: 2190. Gene: tyrs. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (306 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group PBF is 57.14% similar to enzyme reactant L-tyrosine
2j5b
Structure of the tyrosyl tRNA synthetase from acanthamoeba polyphaga mimivirus complexed with tyrosynol
Source: Acanthamoeba polyphaga mimivirus. Organism_taxid: 212035. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plyss.
Chains: A, B (322 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TYE is 92.31% similar to enzyme reactant L-tyrosine
2jan
Tyrosyl-tRNA synthetase from mycobacterium tuberculosis in unliganded state
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Atcc: 25618. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (419 residues) CATH domains: 3.40.50.620 1.10.240.10 3.10.290.10
2pid
Crystal structure of human mitochondrial tyrosyl-tRNA synthe complex with an adenylate analog
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: yars2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (317 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group YSA is 48.72% similar to enzyme product AMP
2pxh
Crystal structure of a bipyridylalanyl-tRNA synthetase
Source: Methanocaldococcus jannaschii. Organism_taxid: 2190. Gene: tyrosyl-tRNA synthetase. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (306 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group BP5 is 63.16% similar to enzyme reactant L-tyrosine
2q1g
Crystal structure of 4-(trifluoromethyldiazirinyl) phenylalanyl-tRNA synthetase
Source: Methanococcus jannaschii. Gene: tyrs. Expressed in: escherichia coli.
Chain: A (306 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group T11 is 60.00% similar to enzyme reactant L-tyrosine
2q1i
Crystal structure of 4-(trifluoromethyldiazirinyl) phenylalanyl-tRNA synthetase
Source: Methanococcus jannaschii. Gene: tyrs. Expressed in: escherichia coli.
Chain: A (308 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TFQ is 66.00% similar to enzyme reactant L-tyrosine
2rkj
Cocrystal structure of a tyrosyl-tRNA synthetase splicing factor with a group i intron RNA
Source: Neurospora crassa. Organism_taxid: 5141. Gene: cyt-18. Expressed in: escherichia coli. Expression_system_taxid: 562. Staphylococcus phage twort. Organism_taxid: 55510. Gene: orf142-i2. Expressed in: staphylococcus phage twort.
Chains: A, B, E, F, I, J, M, N (367 residues)
2ts1
Structure of tyrosyl-t/RNA synthetase refined at 2.3 angstro resolution. Interaction of the enzyme with the tyrosyl aden intermediate
Source: Geobacillus stearothermophilus. Organism_taxid: 1422
Chain: A (317 residues) CATH domains: 3.40.50.620 1.10.240.10
2yxn
Structual basis of azido-tyrosine recognition by engineered tyrosyl-tRNA synthetase
Source: Escherichia coli. Organism_taxid: 316407. Strain: k12 substr. W3110. Gene: tyrs. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (322 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group AZY is 81.25% similar to enzyme reactant L-tyrosine
2zp1
Structual basis of iodo-tyrosine recognition by engineered archeal tyrosyl-tRNA synthetase
Source: Methanocaldococcus jannaschii. Methanococcus jannaschii. Organism_taxid: 2190. Gene: tyrs, mj0389. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (308 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group IYR is 92.00% similar to enzyme reactant L-tyrosine
3d6u
Crystal structure of 4-(trifluoromethyldiazirinyl) phenylalanyl-tRNA synthetase
Source: Methanocaldococcus jannaschii. Organism_taxid: 2190. Gene: tyrs, mj0389. Expressed in: escherichia coli
Chain: A (306 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group T11 is 60.00% similar to enzyme reactant L-tyrosine
3d6v
Crystal structure of 4-(trifluoromethyldiazirinyl) phenylalanyl-tRNA synthetase
Source: Methanocaldococcus jannaschii. Methanococcus jannaschii. Organism_taxid: 2190. Gene: tyrs, mj0389. Expressed in: escherichia coli
Chain: A (308 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TFQ is 66.00% similar to enzyme reactant L-tyrosine
3n2y
Crystal structure of tyrosyl-tRNA synthetase complexed with tetrazolyl)-phenylalanine
Source: Methanocaldococcus jannaschii. Methanococcus jannaschii. Organism_taxid: 2190. Gene: tyrs. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (305 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TEF is 66.00% similar to enzyme reactant L-tyrosine
3p0h
Leishmania major tyrosyl-tRNA synthetase in complex with fis cubic crystal form
Source: Leishmania major. Organism_taxid: 5664. Gene: lmjf14.1370. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (665 residues) CATH domains: Unassigned 3.40.50.620 1.10.240.10
Bound ligand:   Het Group FSE is 47.83% similar to enzyme reactant L-tyrosine
3p0i
Leishmania major tyrosyl-tRNA synthetase in complex with tyr cubic crystal form
Source: Leishmania major. Organism_taxid: 5664. Gene: lmjf14.1370. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (673 residues) CATH domains: Unassigned Unassigned 1.10.240.10
Bound ligand:   Het Group TYE is 92.31% similar to enzyme reactant L-tyrosine
3p0j
Leishmania major tyrosyl-tRNA synthetase in complex with tyr triclinic crystal form 1
Source: Leishmania major. Organism_taxid: 5664. Gene: lmjf14.1370. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (657 residues) CATH domains: Unassigned 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TYE is 92.31% similar to enzyme reactant L-tyrosine
3qe4
An evolved aminoacyl-tRNA synthetase with atypical polysubst specificity
Source: Methanocaldococcus jannaschii. Methanococcus jannaschii. Organism_taxid: 2190. Gene: mj0389, tyrrs, tyrs. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (307 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group 4CF is 80.00% similar to enzyme reactant L-tyrosine
3ts1
Structure of tyrosyl-t/RNA synthetase refined at 2.3 angstro resolution. Interaction of the enzyme with the tyrosyl aden intermediate
Source: Geobacillus stearothermophilus. Organism_taxid: 1422
Chain: A (317 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TYA is 67.65% similar to enzyme product AMP
3vgj
Crystal of plasmodium falciparum tyrosyl-tRNA synthetase (pf complex with adenylate analog
Source: Plasmodium falciparum. Organism_taxid: 36329. Strain: 3d7. Gene: mal8p1.125. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (353 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group YAP is 65.71% similar to enzyme product AMP
3zxi
Crystal structure of human mitochondrial tyrosyl-tRNA synthetase in complex with a tyrosyl-adenylate analog
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (306 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TYA is 67.65% similar to enzyme product AMP
4hjr
Crystal structure of f2yrs
Source: Methanocaldococcus jannaschii dsm 2661 organism_taxid: 243232. Strain: atcc 43067 / dsm 2661 / jal-1 / jcm 10045 / nbrc 10 gene: tyrs, mj0389. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (309 residues) CATH domains: 3.40.50.620 1.10.240.10
4hjx
Crystal structure of f2yrs complexed with f2y
Source: Methanococcus jannaschii dsm 2661. Organism_taxid: 243232. Strain: atcc 43067 / dsm 2661 / jal-1 / jcm 10045 / nbrc 10 gene: tyrs, mj0389. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (306 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group F2Y is 86.67% similar to enzyme reactant L-tyrosine
4hk4
Crystal structure of apo tyrosine-tRNA ligase mutant protein
Source: Methanocaldococcus jannaschii. Organism_taxid: 2190. Gene: tyrs, mj0389. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (309 residues) CATH domains: 3.40.50.620 1.10.240.10
4hpw
Crystal structure of tyrosine-tRNA ligase mutant complexed w unnatural amino acid 3-o-methyl-tyrosine
Source: Methanocaldococcus jannaschii. Organism_taxid: 243232. Strain: atcc 43067 / dsm 2661 / jal-1 / jcm 10045 / nbrc 10 gene: tyrs, mj0389. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (310 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group 3YM is 86.67% similar to enzyme reactant L-tyrosine
4nd6
Crystal structure of apo 3-nitro-tyrosine tRNA synthetase (5 open form
Source: Methanocaldococcus jannaschii. Organism_taxid: 243232. Strain: atcc 43067 / dsm 2661 / jal-1 / jcm 10045 / nbrc 10 gene: mj0389, tyrs, tyrs mj0389. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (303 residues) CATH domains: 3.40.50.620 1.10.240.10
4nd7
Crystal structure of apo 3-nitro-tyrosine tRNA synthetase (5 closed form
Source: Methanocaldococcus jannaschii. Organism_taxid: 243232. Strain: atcc 43067 / dsm 2661 / jal-1 / jcm 10045 / nbrc 10 gene: mj0389, tyrs, tyrs mj0389. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (310 residues) CATH domains: 3.40.50.620 1.10.240.10
4nda
Crystal structure of 3-nitro-tyrosine tRNA synthetase (5b) b nitro-tyrosine
Source: Methanocaldococcus jannaschii. Organism_taxid: 243232. Strain: atcc 43067 / dsm 2661 / jal-1 / jcm 10045 / nbrc 10 gene: mj0389, tyrs, tyrs mj0389. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (308 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group NIY is 81.25% similar to enzyme reactant L-tyrosine
4ojm
Crystal structure of a c-terminally truncated cyt-18 protein n-terminal residues
Source: Neurospora crassa. Organism_taxid: 367110. Strain: atcc 24698 / 74-or23-1a / cbs 708.71 / dsm 1257 / f or74a. Gene: cyt-18, b18p24.070, ncu03030
Chain: X (382 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TYR corresponds to enzyme reactant L-tyrosine
4pbr
Crystal structure of the m. Jannaschii g2 tRNA synthetase va bound to 4-(2-bromoisobutyramido)-phenylalanine (bibaf)
Source: Methanocaldococcus jannaschii. Organism_taxid: 243232. Strain: atcc 43067 / dsm 2661 / jal-1 / jcm 10045 / nbrc 10 gene: tyrs, mj0389. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (310 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group 2L7 is 60.00% similar to enzyme reactant L-tyrosine
4pbs
Crystal structure of the m. Jannaschii f9 tRNA synthetase va bound to 4-(2-bromoisobutyramido)-phenylalanine (bibaf)
Source: Methanocaldococcus jannaschii. Organism_taxid: 243232. Strain: atcc 43067 / dsm 2661 / jal-1 / jcm 10045 / nbrc 10 gene: tyrs, mj0389. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (310 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group 2L7 is 60.00% similar to enzyme reactant L-tyrosine
4pbt
Crystal structure of the m. Jannaschii g2 tRNA synthetase va bound to 4-trans-cyclooctene-amidopheylalanine (tco-amf)
Source: Methanocaldococcus jannaschii. Organism_taxid: 243232. Strain: atcc 43067 / dsm 2661 / jal-1 / jcm 10045 / nbrc 10 gene: tyrs, mj0389. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (310 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group 2LQ is 50.00% similar to enzyme reactant L-tyrosine
4ts1
Crystal structure of a deletion mutant of a tyrosyl-t/RNA synthetase complexed with tyrosine
Source: Geobacillus stearothermophilus. Organism_taxid: 1422.
Chains: A, B (317 residues) CATH domains: 3.40.50.620 1.10.240.10
Bound ligand:   Het Group TYR corresponds to enzyme reactant L-tyrosine