› 8hzb

Electron Microscopy
3.2Å resolution

Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-1)

Released:
DOI: 10.2210/pdb8hzb/pdb
PDB entry 8hzb coloured by chain, front view.
PDB entry 8hzb coloured by chain, side view.
PDB entry 8hzb coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Tao YQ, Zhao QY, Liu C, Li D
Related structures: EMD-35087

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-synuclein Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 140 amino acids
Theoretical weight: 14.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P37840 (Residues: 1-140; Coverage: 100%)
Gene names: NACP, PARK1, SNCA
Sequence domains: Synuclein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.2Å
Relevant EMDB volumes: EMD-35087
Expression system: Escherichia coli

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