Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero 360-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-235746 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
Capsid protein VP1
Molecule details ›
Chain: 1
Length: 279 amino acids
Theoretical weight: 31.36 KDa
Source organism: Human poliovirus 3 strain Sabin
UniProt:
Length: 279 amino acids
Theoretical weight: 31.36 KDa
Source organism: Human poliovirus 3 strain Sabin
UniProt:
- Canonical:
P03302 (Residues: 600-878; Coverage: 13%)
Capsid protein VP2
Molecule details ›
Chain: 2
Length: 263 amino acids
Theoretical weight: 29.41 KDa
Source organism: Human poliovirus 3 strain Sabin
UniProt:
Length: 263 amino acids
Theoretical weight: 29.41 KDa
Source organism: Human poliovirus 3 strain Sabin
UniProt:
- Canonical: P03302 (Residues: 78-340; Coverage: 12%)
Capsid protein VP3
Molecule details ›
Chain: 3
Length: 235 amino acids
Theoretical weight: 25.95 KDa
Source organism: Human poliovirus 3 strain Sabin
UniProt:
Length: 235 amino acids
Theoretical weight: 25.95 KDa
Source organism: Human poliovirus 3 strain Sabin
UniProt:
- Canonical: P03302 (Residues: 341-575; Coverage: 11%)
Capsid protein VP4
Molecule details ›
Chain: 4
Length: 68 amino acids
Theoretical weight: 7.32 KDa
Source organism: Human poliovirus 3 strain Sabin
UniProt:
Length: 68 amino acids
Theoretical weight: 7.32 KDa
Source organism: Human poliovirus 3 strain Sabin
UniProt:
- Canonical: P03302 (Residues: 2-69; Coverage: 3%)
