› 7tdo

Electron Microscopy
3.15Å resolution

Cryo-EM structure of transmembrane AAA+ protease FtsH in the ADP state

Released:
DOI: 10.2210/pdb7tdo/pdb
PDB entry 7tdo coloured by chain, front view.
PDB entry 7tdo coloured by chain, side view.
PDB entry 7tdo coloured by chain, top view.
Source organism: Thermotoga maritima
Primary publication:
Cryo-EM structure of transmembrane AAA+ protease FtsH in the ADP state.
Liu W, Schoonen M, Wang T, McSweeney S, Liu Q
Commun Biol 5 257 (2022)
PMID: 35322207
Related structures: EMD-25837

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194575 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-dependent zinc metalloprotease FtsH Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 613 amino acids
Theoretical weight: 68.49 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9WZ49 (Residues: 1-610; Coverage: 100%)
Gene names: TM_0580, ftsH
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand ADP 6 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.15Å
Relevant EMDB volumes: EMD-25837
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

Deciphering the mechanism and function of Hsp100 unfoldases from protein structure.
Lee et al. (2022)
2 more

2 mentions without citation

Cryo-EM structure of transmembrane AAA+ protease FtsH in the ADP state.
Liu et al. (2022)
1 more