› 5v94

X-ray diffraction
1.65Å resolution

Pekin duck egg lysozyme isoform III (DEL-III), cubic form

Released:
DOI: 10.2210/pdb5v94/pdb
PDB entry 5v94 coloured by chain, front view.
PDB entry 5v94 coloured by chain, side view.
PDB entry 5v94 coloured by chain, top view.
Source organism: Anas platyrhynchos
Primary publication:
Structural basis of antigen recognition: crystal structure of duck egg lysozyme.
Langley DB, Crossett B, Schofield P, Jackson J, Zeraati M, Maltby D, Christie M, Burnett D, Brink R, Goodnow C, Christ D
Acta Crystallogr D Struct Biol 73 910-920 (2017)
PMID: 29095163

Function and Biology Details

Reaction catalysed: 
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132930 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysozyme C-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 129 amino acids
Theoretical weight: 14.63 KDa
Source organism: Anas platyrhynchos
UniProt:
  • Canonical: P00705 (Residues: 19-147; Coverage: 100%)
Sequence domains: C-type lysozyme/alpha-lactalbumin family
Structure domains: Lysozyme

Ligands and Environments

3 bound ligands:
Ligand PO4 7 x PO4
Ligand MRD 1 x MRD
Ligand TRS 1 x TRS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P213
Unit cell:
a: 95.95Å b: 95.95Å c: 95.95Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.187 0.214

Quick links

Citations

2 citation in other articles

Surface-associated antigen induces permeabilization of primary mouse B-cells and lysosome exocytosis facilitating antigen uptake and presentation to T-cells.
Maeda et al. (2021)
1 more

2 mentions without citation

Structural basis of antigen recognition: crystal structure of duck egg lysozyme.
Langley et al. (2017)
1 more