› 5gpa

X-ray diffraction
2.05Å resolution

Structural analysis of fatty acid degradation regulator FadR from Bacillus halodurans

Released:
DOI: 10.2210/pdb5gpa/pdb
PDB entry 5gpa coloured by chain, front view.
PDB entry 5gpa coloured by chain, side view.
PDB entry 5gpa coloured by chain, top view.
Source organism: Alkalihalobacillus halodurans C-125
Primary publication:
Structural basis of operator sites recognition and effector binding in the TetR family transcription regulator FadR.
Yeo HK, Park YW, Lee JY
Nucleic Acids Res 45 4244-4254 (2017)
PMID: 28160603

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191782 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH tetR-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 195 amino acids
Theoretical weight: 22.33 KDa
Source organism: Alkalihalobacillus halodurans C-125
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9K8A4 (Residues: 1-195; Coverage: 100%)
Gene name: BH3102
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: P3221
Unit cell:
a: 56.393Å b: 56.393Å c: 199.607Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.207 0.204 0.261
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Functional Mechanism of the Efflux Pumps Transcription Regulators From Pseudomonas aeruginosa Based on 3D Structures.
Housseini B Issa et al. (2018)
1 more

7 mentions without citation

High pressure and multiferroics materials: a happy marriage.
Gilioli et al. (2014)
6 more