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Crystal Structure of Human Pseudouridylate Synthase 7

X-ray diffraction
2.26Å resolution
PDB entry 5kkp coloured by chain, front view.
PDB entry 5kkp coloured by chain, side view.
PDB entry 5kkp coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Pseudouridylate synthase 7 homolog
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-188685

Macromolecules

Pseudouridylate synthase 7 homolog
Chain: A
Length: 563 amino acids
Theoretical weight: 65.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96PZ0 (Residues: 99-661; Coverage: 85%)
Gene names: KIAA1897, PUS7
Pfam: tRNA pseudouridine synthase D (TruD)
InterPro:
Pseudouridylate synthase 7 homolog in PDB entry 5kkp, assembly 1, front view.
Pseudouridylate synthase 7 homolog in PDB entry 5kkp, assembly 1, side view.
Pseudouridylate synthase 7 homolog in PDB entry 5kkp, assembly 1, top view.
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