› 4zb6

X-ray diffraction
1.8Å resolution

Crystal structure of glutathione transferase URE2P4 from Phanerochaete chrysosporium in complex with oxidized glutathione.

Released:
DOI: 10.2210/pdb4zb6/pdb
PDB entry 4zb6 coloured by chain, front view.
PDB entry 4zb6 coloured by chain, side view.
PDB entry 4zb6 coloured by chain, top view.
Source organism: Phanerodontia chrysosporium
Primary publication:
Evolutionary divergence of Ure2pA glutathione transferases in wood degrading fungi.
Roret T, Thuillier A, Favier F, Gelhaye E, Didierjean C, Morel-Rouhier M
Fungal Genet Biol 83 103-112 (2015)
PMID: 26348000

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-102632 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 223 amino acids
Theoretical weight: 25.65 KDa
Source organism: Phanerodontia chrysosporium
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0R4I980 (Residues: 1-223; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand GDS 4 x GDS
Ligand NA 4 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: P212121
Unit cell:
a: 92.437Å b: 94.059Å c: 104.627Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.165 0.163 0.19
Expression system: Escherichia coli

Quick links

Citations

11 citation in other articles

Conserved white-rot enzymatic mechanism for wood decay in the Basidiomycota genus Pycnoporus.
Miyauchi et al. (2020)
10 more

1 mention without citation

Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin.
Scherlach et al. (2021)