› 4m4g

X-ray diffraction
2.7Å resolution

Crystal structure of ligand binding domain of CysB, a LysR member from Salmonella typhimurium LT2 in complex with effector ligand, N-acetylserine.

Released:
DOI: 10.2210/pdb4m4g/pdb
PDB entry 4m4g coloured by chain, front view.
PDB entry 4m4g coloured by chain, side view.
PDB entry 4m4g coloured by chain, top view.
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Entry authors: Mittal M, Singh AK, Kumaran S

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139097 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH-type transcriptional regulator CysB Chain: A
Molecule details ›
Chain: A
Length: 245 amino acids
Theoretical weight: 27.52 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Expression system: Escherichia coli
UniProt:
  • Canonical: P06614 (Residues: 86-324; Coverage: 74%)
Gene names: STM1713, cysB
Sequence domains: LysR substrate binding domain
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

2 bound ligands:
Ligand SAC 2 x SAC
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: C2221
Unit cell:
a: 57.736Å b: 74.3Å c: 104.732Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.219 0.276
Expression system: Escherichia coli

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