PDBe 4c0u

Electron Microscopy
10Å resolution

Cryo-EM reconstruction of enterovirus 71 in complex with a neutralizing antibody E18

Released:
Source organisms:
Related structures: EMD-2397

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assemblies composition:
hetero 300-mer (preferred)
hetero pentamer
hetero 25-mer
hetero 30-mer
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
VP1 Chain: A
Molecule details ›
Chain: A
Length: 298 amino acids
Theoretical weight: 32.83 KDa
Source organism: Enterovirus A71
UniProt:
  • Canonical: A9X4C2 (Residues: 566-863; Coverage: 14%)
Sequence domains: picornavirus capsid protein
VP2 Chain: B
Molecule details ›
Chain: B
Length: 254 amino acids
Theoretical weight: 27.8 KDa
Source organism: Enterovirus A71
UniProt:
  • Canonical: A9X4C2 (Residues: 70-323; Coverage: 12%)
Sequence domains: picornavirus capsid protein
VP3 Chain: C
Molecule details ›
Chain: C
Length: 242 amino acids
Theoretical weight: 26.52 KDa
Source organism: Enterovirus A71
UniProt:
  • Canonical: A9X4C2 (Residues: 324-565; Coverage: 11%)
Sequence domains: picornavirus capsid protein
FAB EV18 4 D6-1 F1 G9 Chain: Y
Molecule details ›
Chain: Y
Length: 217 amino acids
Theoretical weight: 18.49 KDa
Source organism: Mus musculus
FAB EV18 4 D6-1 F1 G9 Chain: Z
Molecule details ›
Chain: Z
Length: 220 amino acids
Theoretical weight: 18.74 KDa
Source organism: Mus musculus

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 10Å
Relevant EMDB volumes: EMD-2397