› › Function and Biology

The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a novel SOUBA domain

Source organism: Homo sapiens
Biochemical function: ubiquitin binding
Biological process: ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
Cellular component: ESCRT I complex

Quick links

GO terms

Sequence family

Pfam Protein family (Pfam)
PF21267
Domain description: Ubiquitin-associated protein 1, UBA2 domain
Occurring in:
  1. Ubiquitin-associated protein 1
  2. Ubiquitin-associated protein 1

InterPro InterPro annotations
IPR015940
Domain description: Ubiquitin-associated domain
Occurring in:
  1. Ubiquitin-associated protein 1
  2. Ubiquitin-associated protein 1
IPR009060
Domain description: UBA-like superfamily
Occurring in:
  1. Ubiquitin-associated protein 1
  2. Ubiquitin-associated protein 1
IPR038870
Domain description: Ubiquitin-associated protein 1
Occurring in:
  1. Ubiquitin-associated protein 1
  2. Ubiquitin-associated protein 1
IPR042575
Domain description: Ubiquitin-associated protein 1, C-terminal
Occurring in:
  1. Ubiquitin-associated protein 1
  2. Ubiquitin-associated protein 1

Structure domain

CATH CATH domain
1.20.120.1920
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Four Helix Bundle (Hemerythrin (Met), subunit A)
Homology: UBAP1 SOUBA domain
Occurring in:
  1. Ubiquitin-associated protein 1
  2. Ubiquitin-associated protein 1
The deposited structure of PDB entry 4ae4 contains 1 copy of CATH domain 1.20.120.1920 (Four Helix Bundle (Hemerythrin (Met), subunit A)) in Ubiquitin-associated protein 1. Showing 1 copy in chain A.
The deposited structure of PDB entry 4ae4 contains 1 copy of CATH domain 1.20.120.1920 (Four Helix Bundle (Hemerythrin (Met), subunit A)) in Ubiquitin-associated protein 1. Showing 1 copy in chain B.

Quick links