3rlf Citations

Snapshots of the maltose transporter during ATP hydrolysis.

Proc Natl Acad Sci U S A 108 15152-6 (2011)
Related entries: 3puv, 3puw, 3pux

Cited: 123 times
EuropePMC logo PMID: 21825153

Abstract

ATP-binding cassette transporters are powered by ATP, but the mechanism by which these transporters hydrolyze ATP is unclear. In this study, four crystal structures of the full-length wild-type maltose transporter, stabilized by adenosine 5'-(β,γ-imido)triphosphate or ADP in conjunction with phosphate analogs BeF(3)(-), VO(4)(3-), or AIF(4)(-), were determined to 2.2- to 2.4-Å resolution. These structures led to the assignment of two enzymatic states during ATP hydrolysis and demonstrate specific functional roles of highly conserved residues in the nucleotide-binding domain, suggesting that ATP-binding cassette transporters catalyze ATP hydrolysis via a general base mechanism.

Reviews - 3rlf mentioned but not cited (5)

  1. Structural diversity of ABC transporters. ter Beek J, Guskov A, Slotboom DJ. J Gen Physiol 143 419-435 (2014)
  2. Influences of membrane mimetic environments on membrane protein structures. Zhou HX, Cross TA. Annu Rev Biophys 42 361-392 (2013)
  3. Structural and functional diversity calls for a new classification of ABC transporters. Thomas C, Aller SG, Beis K, Carpenter EP, Chang G, Chen L, Dassa E, Dean M, Duong Van Hoa F, Ekiert D, Ford R, Gaudet R, Gong X, Holland IB, Huang Y, Kahne DK, Kato H, Koronakis V, Koth CM, Lee Y, Lewinson O, Lill R, Martinoia E, Murakami S, Pinkett HW, Poolman B, Rosenbaum D, Sarkadi B, Schmitt L, Schneider E, Shi Y, Shyng SL, Slotboom DJ, Tajkhorshid E, Tieleman DP, Ueda K, Váradi A, Wen PC, Yan N, Zhang P, Zheng H, Zimmer J, Tampé R. FEBS Lett 594 3767-3775 (2020)
  4. An integrated transport mechanism of the maltose ABC importer. Mächtel R, Narducci A, Griffith DA, Cordes T, Orelle C. Res Microbiol 170 321-337 (2019)
  5. ATP Analogues for Structural Investigations: Case Studies of a DnaB Helicase and an ABC Transporter. Lacabanne D, Wiegand T, Wili N, Kozlova MI, Cadalbert R, Klose D, Mulkidjanian AY, Meier BH, Böckmann A. Molecules 25 E5268 (2020)

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  1. Snapshots of the maltose transporter during ATP hydrolysis. Oldham ML, Chen J. Proc Natl Acad Sci U S A 108 15152-15156 (2011)
  2. Multiscale Simulations of Biological Membranes: The Challenge To Understand Biological Phenomena in a Living Substance. Enkavi G, Javanainen M, Kulig W, Róg T, Vattulainen I. Chem Rev 119 5607-5774 (2019)
  3. Architecture of a channel-forming O-antigen polysaccharide ABC transporter. Bi Y, Mann E, Whitfield C, Zimmer J. Nature 553 361-365 (2018)
  4. Structural basis for substrate specificity in the Escherichia coli maltose transport system. Oldham ML, Chen S, Chen J. Proc Natl Acad Sci U S A 110 18132-18137 (2013)
  5. Inferring interaction partners from protein sequences using mutual information. Bitbol AF. PLoS Comput Biol 14 e1006401 (2018)
  6. Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation. Kolich LR, Chang YT, Coudray N, Giacometti SI, MacRae MR, Isom GL, Teran EM, Bhabha G, Ekiert DC. Elife 9 e60030 (2020)
  7. Regulatory mechanisms of lipopolysaccharide synthesis in Escherichia coli. Shu S, Mi W. Nat Commun 13 4576 (2022)
  8. Correlations from structure and phylogeny combine constructively in the inference of protein partners from sequences. Gerardos A, Dietler N, Bitbol AF. PLoS Comput Biol 18 e1010147 (2022)
  9. ATP hydrolysis and nucleotide exit enhance maltose translocation in the MalFGK2E importer. Abreu B, Cruz C, Oliveira ASF, Soares CM. Sci Rep 11 10591 (2021)
  10. Protein Modification Employing Non-Canonical Amino Acids to Prepare SUMOylation Detecting Bioconjugates. Williard AC, Switzer HJ, Howard CA, Yin R, Russell BL, Sanyal R, Yu S, Myers TM, Flood BM, Kerscher O, Young DD. Pharmaceutics 14 2826 (2022)


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  1. Structure and mechanism of ABC transporters. Wilkens S. F1000Prime Rep 7 14 (2015)
  2. Transport of sugars. Chen LQ, Cheung LS, Feng L, Tanner W, Frommer WB. Annu Rev Biochem 84 865-894 (2015)
  3. A glimpse of structural biology through X-ray crystallography. Shi Y. Cell 159 995-1014 (2014)
  4. The Type 1 secretion pathway - the hemolysin system and beyond. Thomas S, Holland IB, Schmitt L. Biochim Biophys Acta 1843 1629-1641 (2014)
  5. Molecular mechanism of the Escherichia coli maltose transporter. Chen J. Curr Opin Struct Biol 23 492-498 (2013)
  6. Clinically-Relevant ABC Transporter for Anti-Cancer Drug Resistance. Xiao H, Zheng Y, Ma L, Tian L, Sun Q. Front Pharmacol 12 648407 (2021)
  7. Mechanism of Action of ABC Importers: Conservation, Divergence, and Physiological Adaptations. Lewinson O, Livnat-Levanon N. J Mol Biol 429 606-619 (2017)
  8. ABC Transport Proteins in Cardiovascular Disease-A Brief Summary. Schumacher T, Benndorf RA. Molecules 22 E589 (2017)
  9. Invited review: Architectures and mechanisms of ATP binding cassette proteins. Hopfner KP. Biopolymers 105 492-504 (2016)
  10. Structure and mechanism of ATP-dependent phospholipid transporters. López-Marqués RL, Poulsen LR, Bailly A, Geisler M, Pomorski TG, Palmgren MG. Biochim Biophys Acta 1850 461-475 (2015)
  11. Visualizing functional motions of membrane transporters with molecular dynamics simulations. Shaikh SA, Li J, Enkavi G, Wen PC, Huang Z, Tajkhorshid E. Biochemistry 52 569-587 (2013)
  12. ECF-Type ATP-Binding Cassette Transporters. Rempel S, Stanek WK, Slotboom DJ. Annu Rev Biochem 88 551-576 (2019)
  13. Structure and mechanism of energy-coupling factor transporters. Zhang P. Trends Microbiol 21 652-659 (2013)
  14. Active transporters as enzymes: an energetic framework applied to major facilitator superfamily and ABC importer systems. Shilton BH. Biochem J 467 193-199 (2015)
  15. Biophysical Approaches Facilitate Computational Drug Discovery for ATP-Binding Cassette Proteins. Molinski SV, Bozóky Z, Iram SH, Ahmadi S. Int J Med Chem 2017 1529402 (2017)
  16. The Switch and Reciprocating Models for the Function of ABC Multidrug Exporters: Perspectives on Recent Research. Jones PM, George AM. Int J Mol Sci 24 2624 (2023)
  17. Functional Roles of the Conserved Amino Acid Sequence Motif C, the Antiporter Motif, in Membrane Transporters of the Major Facilitator Superfamily. Varela MF, Ortiz-Alegria A, Lekshmi M, Stephen J, Kumar S. Biology (Basel) 12 1336 (2023)
  18. How Cryo-EM Has Expanded Our Understanding of Membrane Transporters. Baril SA, Gose T, Schuetz JD. Drug Metab Dispos 51 904-922 (2023)

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  1. Structural Basis of Substrate Recognition by the Multidrug Resistance Protein MRP1. Johnson ZL, Chen J. Cell 168 1075-1085.e9 (2017)
  2. Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation. Hohl M, Briand C, Grütter MG, Seeger MA. Nat Struct Mol Biol 19 395-402 (2012)
  3. Conformation space of a heterodimeric ABC exporter under turnover conditions. Hofmann S, Januliene D, Mehdipour AR, Thomas C, Stefan E, Brüchert S, Kuhn BT, Geertsma ER, Hummer G, Tampé R, Moeller A. Nature 571 580-583 (2019)
  4. On the origin of large flexibility of P-glycoprotein in the inward-facing state. Wen PC, Verhalen B, Wilkens S, Mchaourab HS, Tajkhorshid E. J Biol Chem 288 19211-19220 (2013)
  5. Structural basis of lipopolysaccharide extraction by the LptB2FGC complex. Li Y, Orlando BJ, Liao M. Nature 567 486-490 (2019)
  6. Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter. Hohl M, Hürlimann LM, Böhm S, Schöppe J, Grütter MG, Bordignon E, Seeger MA. Proc Natl Acad Sci U S A 111 11025-11030 (2014)
  7. Structural and mechanistic insights into prokaryotic energy-coupling factor transporters. Slotboom DJ. Nat Rev Microbiol 12 79-87 (2014)
  8. Decoupling catalytic activity from biological function of the ATPase that powers lipopolysaccharide transport. Sherman DJ, Lazarus MB, Murphy L, Liu C, Walker S, Ruiz N, Kahne D. Proc Natl Acad Sci U S A 111 4982-4987 (2014)
  9. Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter. Grossmann N, Vakkasoglu AS, Hulpke S, Abele R, Gaudet R, Tampé R. Nat Commun 5 5419 (2014)
  10. Structure of the 40S-ABCE1 post-splitting complex in ribosome recycling and translation initiation. Heuer A, Gerovac M, Schmidt C, Trowitzsch S, Preis A, Kötter P, Berninghausen O, Becker T, Beckmann R, Tampé R. Nat Struct Mol Biol 24 453-460 (2017)
  11. Dynamic ligand-induced conformational rearrangements in P-glycoprotein as probed by fluorescence resonance energy transfer spectroscopy. Verhalen B, Ernst S, Börsch M, Wilkens S. J Biol Chem 287 1112-1127 (2012)
  12. Mechanism of allosteric modulation of P-glycoprotein by transport substrates and inhibitors. Dastvan R, Mishra S, Peskova YB, Nakamoto RK, Mchaourab HS. Science 364 689-692 (2019)
  13. Catalytic transitions in the human MDR1 P-glycoprotein drug binding sites. Wise JG. Biochemistry 51 5125-5141 (2012)
  14. Structure of a bacterial energy-coupling factor transporter. Wang T, Fu G, Pan X, Wu J, Gong X, Wang J, Shi Y. Nature 497 272-276 (2013)
  15. Transmembrane gate movements in the type II ATP-binding cassette (ABC) importer BtuCD-F during nucleotide cycle. Joseph B, Jeschke G, Goetz BA, Locher KP, Bordignon E. J Biol Chem 286 41008-41017 (2011)
  16. Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG. Dong H, Zhang Z, Tang X, Paterson NG, Dong C. Nat Commun 8 222 (2017)
  17. Antibiotic resistance ABCF proteins reset the peptidyl transferase centre of the ribosome to counter translational arrest. Murina V, Kasari M, Hauryliuk V, Atkinson GC. Nucleic Acids Res 46 3753-3763 (2018)
  18. ATPase activity of human ABCG1 is stimulated by cholesterol and sphingomyelin. Hirayama H, Kimura Y, Kioka N, Matsuo M, Ueda K. J Lipid Res 54 496-502 (2013)
  19. Molecular Mechanism of ATP Hydrolysis in an ABC Transporter. Prieß M, Göddeke H, Groenhof G, Schäfer LV. ACS Cent Sci 4 1334-1343 (2018)
  20. Plant Lessons: Exploring ABCB Functionality Through Structural Modeling. Bailly A, Yang H, Martinoia E, Geisler M, Murphy AS. Front Plant Sci 2 108 (2011)
  21. Structural insight in the toppling mechanism of an energy-coupling factor transporter. Swier LJ, Guskov A, Slotboom DJ. Nat Commun 7 11072 (2016)
  22. Structure of a pantothenate transporter and implications for ECF module sharing and energy coupling of group II ECF transporters. Zhang M, Bao Z, Zhao Q, Guo H, Xu K, Wang C, Zhang P. Proc Natl Acad Sci U S A 111 18560-18565 (2014)
  23. Inward facing conformations of the MetNI methionine ABC transporter: Implications for the mechanism of transinhibition. Johnson E, Nguyen PT, Yeates TO, Rees DC. Protein Sci 21 84-96 (2012)
  24. Stepwise 5' DNA end-specific resection of DNA breaks by the Mre11-Rad50-Xrs2 and Sae2 nuclease ensemble. Cannavo E, Reginato G, Cejka P. Proc Natl Acad Sci U S A 116 5505-5513 (2019)
  25. Structural basis for transcription complex disruption by the Mfd translocase. Kang JY, Llewellyn E, Chen J, Olinares PDB, Brewer J, Chait BT, Campbell EA, Darst SA. Elife 10 e62117 (2021)
  26. Conformational plasticity of the type I maltose ABC importer. Böhm S, Licht A, Wuttge S, Schneider E, Bordignon E. Proc Natl Acad Sci U S A 110 5492-5497 (2013)
  27. Structural basis for substrate specificity of an amino acid ABC transporter. Yu J, Ge J, Heuveling J, Schneider E, Yang M. Proc Natl Acad Sci U S A 112 5243-5248 (2015)
  28. Structure of a Type-1 Secretion System ABC Transporter. Morgan JLW, Acheson JF, Zimmer J. Structure 25 522-529 (2017)
  29. ATP alone triggers the outward facing conformation of the maltose ATP-binding cassette transporter. Bao H, Duong F. J Biol Chem 288 3439-3448 (2013)
  30. Structural analysis of bacterial ABC transporter inhibition by an antibody fragment. Ahuja S, Rougé L, Swem DL, Sudhamsu J, Wu P, Russell SJ, Alexander MK, Tam C, Nishiyama M, Starovasnik MA, Koth CM. Structure 23 713-723 (2015)
  31. Structure of a Bacterial ABC Transporter Involved in the Import of an Acidic Polysaccharide Alginate. Maruyama Y, Itoh T, Kaneko A, Nishitani Y, Mikami B, Hashimoto W, Murata K. Structure 23 1643-1654 (2015)
  32. Full engagement of liganded maltose-binding protein stabilizes a semi-open ATP-binding cassette dimer in the maltose transporter. Alvarez FJ, Orelle C, Huang Y, Bajaj R, Everly RM, Klug CS, Davidson AL. Mol Microbiol 98 878-894 (2015)
  33. Translocation mechanism of P-glycoprotein and conformational changes occurring at drug-binding site: Insights from multi-targeted molecular dynamics. Prajapati R, Sangamwar AT. Biochim Biophys Acta 1838 2882-2898 (2014)
  34. Cysteine accessibility probes timing and extent of NBD separation along the dimer interface in gating CFTR channels. Chaves LA, Gadsby DC. J Gen Physiol 145 261-283 (2015)
  35. Reinterpreting the action of ATP analogs on K(ATP) channels. Ortiz D, Gossack L, Quast U, Bryan J. J Biol Chem 288 18894-18902 (2013)
  36. Generating symmetry in the asymmetric ATP-binding cassette (ABC) transporter Pdr5 from Saccharomyces cerevisiae. Gupta RP, Kueppers P, Hanekop N, Schmitt L. J Biol Chem 289 15272-15279 (2014)
  37. Direct Spectroscopic Detection of ATP Turnover Reveals Mechanistic Divergence of ABC Exporters. Collauto A, Mishra S, Litvinov A, Mchaourab HS, Goldfarb D. Structure 25 1264-1274.e3 (2017)
  38. Flexible-to-rigid transition is central for substrate transport in the ABC transporter BmrA from Bacillus subtilis. Lacabanne D, Orelle C, Lecoq L, Kunert B, Chuilon C, Wiegand T, Ravaud S, Jault JM, Meier BH, Böckmann A. Commun Biol 2 149 (2019)
  39. Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5. Harris A, Wagner M, Du D, Raschka S, Nentwig LM, Gohlke H, Smits SHJ, Luisi BF, Schmitt L. Nat Commun 12 5254 (2021)
  40. ATP-dependent Conformational Changes Trigger Substrate Capture and Release by an ECF-type Biotin Transporter. Finkenwirth F, Sippach M, Landmesser H, Kirsch F, Ogienko A, Grunzel M, Kiesler C, Steinhoff HJ, Schneider E, Eitinger T. J Biol Chem 290 16929-16942 (2015)
  41. Topological in vitro loading of the budding yeast cohesin ring onto DNA. Minamino M, Higashi TL, Bouchoux C, Uhlmann F. Life Sci Alliance 1 (2018)
  42. Tuning the drug efflux activity of an ABC transporter in vivo by in vitro selected DARPin binders. Seeger MA, Mittal A, Velamakanni S, Hohl M, Schauer S, Salaa I, Grütter MG, van Veen HW. PLoS One 7 e37845 (2012)
  43. Analyses of conformational states of the transporter associated with antigen processing (TAP) protein in a native cellular membrane environment. Geng J, Sivaramakrishnan S, Raghavan M. J Biol Chem 288 37039-37047 (2013)
  44. Large-scale purification of functional human P-glycoprotein (ABCB1). Nandigama K, Lusvarghi S, Shukla S, Ambudkar SV. Protein Expr Purif 159 60-68 (2019)
  45. Unidirectional Transport Mechanism in an ATP Dependent Exporter. Xu Y, Seelig A, Bernèche S. ACS Cent Sci 3 250-258 (2017)
  46. A structural framework for unidirectional transport by a bacterial ABC exporter. Fan C, Kaiser JT, Rees DC. Proc Natl Acad Sci U S A 117 19228-19236 (2020)
  47. Role of the two structural domains from the periplasmic Escherichia coli histidine-binding protein HisJ. Chu BC, DeWolf T, Vogel HJ. J Biol Chem 288 31409-31422 (2013)
  48. Sequential Action of MalE and Maltose Allows Coupling ATP Hydrolysis to Translocation in the MalFGK2 Transporter. Bao H, Dalal K, Cytrynbaum E, Duong F. J Biol Chem 290 25452-25460 (2015)
  49. Structure-function relations in the NTPase domain of the antiviral tRNA ribotoxin Escherichia coli PrrC. Meineke B, Shuman S. Virology 427 144-150 (2012)
  50. Substrate transport activation is mediated through second periplasmic loop of transmembrane protein MalF in maltose transport complex of Escherichia coli. Jacso T, Schneider E, Rupp B, Reif B. J Biol Chem 287 17040-17049 (2012)
  51. Negative Stain Single-particle EM of the Maltose Transporter in Nanodiscs Reveals Asymmetric Closure of MalK2 and Catalytic Roles of ATP, MalE, and Maltose. Fabre L, Bao H, Innes J, Duong F, Rouiller I. J Biol Chem 292 5457-5464 (2017)
  52. Reaction chemistry ABC-style. Senior AE. Proc Natl Acad Sci U S A 108 15015-15016 (2011)
  53. Evidence for a molecular diode-based mechanism in a multispecific ATP-binding cassette (ABC) exporter: SER-1368 as a gatekeeping residue in the yeast multidrug transporter Pdr5. Mehla J, Ernst R, Moore R, Wakschlag A, Marquis MK, Ambudkar SV, Golin J. J Biol Chem 289 26597-26606 (2014)
  54. ATP-dependent interactions of a cargo protein with the transmembrane domain of a polypeptide processing and secretion ABC transporter. Rahman S, Mchaourab HS. J Biol Chem 295 14678-14685 (2020)
  55. Clamping of DNA shuts the condensin neck gate. Lee BG, Rhodes J, Löwe J. Proc Natl Acad Sci U S A 119 e2120006119 (2022)
  56. Purification of the cystic fibrosis transmembrane conductance regulator protein expressed in Saccharomyces cerevisiae. Pollock N, Cant N, Rimington T, Ford RC. J Vis Exp (2014)
  57. Small substrate transport and mechanism of a molybdate ATP binding cassette transporter in a lipid environment. Rice AJ, Harrison A, Alvarez FJ, Davidson AL, Pinkett HW. J Biol Chem 289 15005-15013 (2014)
  58. Substrate recognition and ATPase activity of the E. coli cysteine/cystine ABC transporter YecSC-FliY. Sabrialabed S, Yang JG, Yariv E, Ben-Tal N, Lewinson O. J Biol Chem 295 5245-5256 (2020)
  59. Conformational changes of the histidine ATP-binding cassette transporter studied by double electron-electron resonance spectroscopy. Sippach M, Weidlich D, Klose D, Abé C, Klare J, Schneider E, Steinhoff HJ. Biochim Biophys Acta 1838 1760-1768 (2014)
  60. Conserved Walker A cysteines 431 and 1074 in human P-glycoprotein are accessible to thiol-specific agents in the apo and ADP-vanadate trapped conformations. Sim HM, Bhatnagar J, Chufan EE, Kapoor K, Ambudkar SV. Biochemistry 52 7327-7338 (2013)
  61. Cryo-EM structure of the full-length WzmWzt ABC transporter required for lipid-linked O antigen transport. Caffalette CA, Zimmer J. Proc Natl Acad Sci U S A 118 e2016144118 (2021)
  62. Mutating the Conserved Q-loop Glutamine 1291 Selectively Disrupts Adenylate Kinase-dependent Channel Gating of the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Reduces Channel Function in Primary Human Airway Epithelia. Dong Q, Ernst SE, Ostedgaard LS, Shah VS, Ver Heul AR, Welsh MJ, Randak CO. J Biol Chem 290 14140-14153 (2015)
  63. Spectroscopic glimpses of the transition state of ATP hydrolysis trapped in a bacterial DnaB helicase. Malär AA, Wili N, Völker LA, Kozlova MI, Cadalbert R, Däpp A, Weber ME, Zehnder J, Jeschke G, Eckert H, Böckmann A, Klose D, Mulkidjanian AY, Meier BH, Wiegand T. Nat Commun 12 5293 (2021)
  64. The full-length structure of Thermus scotoductus OLD defines the ATP hydrolysis properties and catalytic mechanism of Class 1 OLD family nucleases. Schiltz CJ, Adams MC, Chappie JS. Nucleic Acids Res 48 2762-2776 (2020)
  65. Allosteric transitions of the maltose transporter studied by an elastic network model. Li CH, Yang YX, Su JG, Liu B, Tan JJ, Zhang XY, Wang CX. Biopolymers 101 758-768 (2014)
  66. Census of halide-binding sites in protein structures. Skitchenko RK, Usoltsev D, Uspenskaya M, Kajava AV, Guskov A. Bioinformatics 36 3064-3071 (2020)
  67. Dual nucleotide specificity determinants of an infection aborting anticodon nuclease. Krutkina E, Klaiman D, Margalit T, Jerabeck-Willemsen M, Kaufmann G. Virology 487 260-272 (2016)
  68. Demonstration of phosphoryl group transfer indicates that the ATP-binding cassette (ABC) transporter cystic fibrosis transmembrane conductance regulator (CFTR) exhibits adenylate kinase activity. Randak CO, Ver Heul AR, Welsh MJ. J Biol Chem 287 36105-36110 (2012)
  69. Does the ATP-bound EQ mutant reflect the pre- or post-ATP hydrolysis state in the catalytic cycle of human P-glycoprotein (ABCB1)? Lusvarghi S, Durell SR, Ambudkar SV. FEBS Lett 595 750-762 (2021)
  70. Interfaces Between Alpha-helical Integral Membrane Proteins: Characterization, Prediction, and Docking. Li B, Mendenhall J, Meiler J. Comput Struct Biotechnol J 17 699-711 (2019)
  71. Maltose-binding protein effectively stabilizes the partially closed conformation of the ATP-binding cassette transporter MalFGK2. Weng J, Gu S, Gao X, Huang X, Wang W. Phys Chem Chem Phys 19 9366-9373 (2017)
  72. Role of cis-trans proline isomerization in the function of pathogenic enterobacterial Periplasmic Binding Proteins. Cortes-Hernandez P, Domínguez-Ramírez L. PLoS One 12 e0188935 (2017)
  73. Conformational Dynamics in the Binding-Protein-Independent Mutant of the Escherichia coli Maltose Transporter, MalG511, and Its Interaction with Maltose Binding Protein. Bajaj R, Park MI, Stauffacher CV, Davidson AL. Biochemistry 57 3003-3015 (2018)
  74. Population level analysis of evolved mutations underlying improvements in plant hemicellulose and cellulose fermentation by Clostridium phytofermentans. Mukherjee S, Thompson LK, Godin S, Schackwitz W, Lipzen A, Martin J, Blanchard JL. PLoS One 9 e86731 (2014)
  75. Release of Entropic Spring Reveals Conformational Coupling Mechanism in the ABC Transporter BtuCD-F. Prieß M, Schäfer LV. Biophys J 110 2407-2418 (2016)
  76. The regulatory domains of the lipid exporter ABCA1 form domain swapped latches. Aller SG, Segrest JP. PLoS One 17 e0262746 (2022)
  77. A specific interdomain interaction preserves the structural and binding properties of the ModA protein from the phytopathogen Xanthomonas citri domain interaction and transport in ModA. Santacruz-Perez C, Pegos VR, Honorato RV, Verli H, Lindahl E, Barbosa JA, Balan A. Arch Biochem Biophys 539 20-30 (2013)
  78. Solid-State NMR Reveals Asymmetric ATP Hydrolysis in the Multidrug ABC Transporter BmrA. Lacabanne D, Wiegand T, Di Cesare M, Orelle C, Ernst M, Jault JM, Meier BH, Böckmann A. J Am Chem Soc 144 12431-12442 (2022)
  79. Structures of prokaryotic ubiquitin-like protein Pup in complex with depupylase Dop reveal the mechanism of catalytic phosphate formation. Cui H, Müller AU, Leibundgut M, Tian J, Ban N, Weber-Ban E. Nat Commun 12 6635 (2021)
  80. The Structure and Mechanism of Drug Transporters. Roberts AG. Methods Mol Biol 2342 193-234 (2021)
  81. Allosteric effects of ATP binding on the nucleotide-binding domain of a heterodimeric ATP-binding cassette transporter. Pan X, Zhang Q, Qu S, Huang S, Wang H, Mei H. Integr Biol (Camb) 8 1158-1169 (2016)
  82. Bacteria with a mouth: Discovery and new insights into cell surface structure and macromolecule transport. Murata K, Kawai S, Hashimoto W. Proc Jpn Acad Ser B Phys Biol Sci 98 529-552 (2022)
  83. Binding Specificity of a Novel Cyclo/Maltodextrin-Binding Protein and Its Role in the Cyclodextrin ABC Importer System from Thermoanaerobacterales. Aranda-Caraballo J, Saenz RA, López-Zavala AA, Velazquez-Cruz B, Espinosa-Barrera L, Cárdenas-Conejo Y, Zárate-Romero A, Linares-Vergara O, Osuna-Castro JA, Bonales-Alatorre E, Centeno-Leija S, Serrano-Posada H. Molecules 28 6080 (2023)
  84. Cholesterol accumulation in ovarian follicles causes ovulation defects in Abca1a -/- Japanese medaka (Oryzias latipes). Futamata R, Kinoshita M, Ogiwara K, Kioka N, Ueda K. Heliyon 9 e13291 (2023)
  85. Historical Article Classic Spotlight: Journal of Bacteriology Minireviews Illuminate Bacterial Translocation Systems. Christie PJ. J Bacteriol 198 3042-3043 (2016)
  86. Common Mechanism of Activated Catalysis in P-loop Fold Nucleoside Triphosphatases-United in Diversity. Kozlova MI, Shalaeva DN, Dibrova DV, Mulkidjanian AY. Biomolecules 12 1346 (2022)
  87. Common Patterns of Hydrolysis Initiation in P-loop Fold Nucleoside Triphosphatases. Kozlova MI, Shalaeva DN, Dibrova DV, Mulkidjanian AY. Biomolecules 12 1345 (2022)
  88. Coupling between ATP hydrolysis and protein conformational change in maltose transporter. Lv X, Liu H, Chen H, Gong H. Proteins 85 207-220 (2017)
  89. Tandem Mass Tags Quantitative Proteome Identification and Function Analysis of ABC Transporters in Neofusicoccum parvum. Chen J, Han S, Li S, Zhu H, Li S, Yan J, Zhu T. Int J Mol Sci 23 9908 (2022)
  90. W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state. Lee SS, Park JG, Jang E, Choi SH, Kim S, Kim JW, Jin MS. Commun Biol 6 960 (2023)