Assemblies
Assembly Name:
Tyrosine-protein kinase ABL2
Multimeric state:
monomeric
Accessible surface area:
13920.32 Å2
Buried surface area:
2014.47 Å2
Dissociation area:
447.73
Å2
Dissociation energy (ΔGdiss):
-0.66
kcal/mol
Dissociation entropy (TΔSdiss):
5.72
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-154850
Assembly Name:
Tyrosine-protein kinase ABL2
Multimeric state:
homo dimer
Accessible surface area:
25660.24 Å2
Buried surface area:
6209.35 Å2
Dissociation area:
1,090.2
Å2
Dissociation energy (ΔGdiss):
5.7
kcal/mol
Dissociation entropy (TΔSdiss):
13.23
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-154851
Macromolecules
Chain: A
Length: 292 amino acids
Theoretical weight: 33.54 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
Length: 292 amino acids
Theoretical weight: 33.54 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
P42684 (Residues: 279-546; Coverage: 23%)
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
- Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
- Protein kinase-like domain superfamily
- Protein kinase domain
- Serine-threonine/tyrosine-protein kinase, catalytic domain
- Tyrosine-protein kinase, catalytic domain
- Protein kinase, ATP binding site
- Tyrosine-protein kinase, active site
