Assemblies
Assembly Name:
Pyruvate kinase PKM
Multimeric state:
homo tetramer
Accessible surface area:
67047.61 Å2
Buried surface area:
17664.31 Å2
Dissociation area:
2,026.08
Å2
Dissociation energy (ΔGdiss):
22.13
kcal/mol
Dissociation entropy (TΔSdiss):
15.87
kcal/mol
Symmetry number:
4
PDBe Complex ID:
PDB-CPX-146985
Assembly Name:
Pyruvate kinase PKM
Multimeric state:
homo dimer
Accessible surface area:
34641.66 Å2
Buried surface area:
6467.23 Å2
Dissociation area:
2,818.07
Å2
Dissociation energy (ΔGdiss):
30.72
kcal/mol
Dissociation entropy (TΔSdiss):
14.92
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-146984
Assembly Name:
Pyruvate kinase PKM
Multimeric state:
homo dimer
Accessible surface area:
36458.11 Å2
Buried surface area:
7144.92 Å2
Dissociation area:
2,857.72
Å2
Dissociation energy (ΔGdiss):
36.86
kcal/mol
Dissociation entropy (TΔSdiss):
15.07
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-146984
Macromolecules
Chains: A, B, C, D
Length: 533 amino acids
Theoretical weight: 58.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam:
InterPro:
Length: 533 amino acids
Theoretical weight: 58.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P14618 (Residues: 1-531; Coverage: 100%)
Pfam:
InterPro:
- Pyruvate kinase, C-terminal domain superfamily
- Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily
- Pyruvate kinase
- Pyruvate kinase, barrel
- Pyruvate kinase-like domain superfamily
- Pyruvate kinase-like, insert domain superfamily
- Pyruvate kinase, insert domain superfamily
- Pyruvate kinase, active site
- Pyruvate kinase, C-terminal
