PDBe 2q0l

X-ray diffraction
1.45Å resolution

Helicobacter pylori thioredoxin reductase reduced by sodium dithionite in complex with NADP+

Source organism: Helicobacter pylori 26695
Primary publication:
High-resolution structures of oxidized and reduced thioredoxin reductase from Helicobacter pylori.
Acta Crystallogr. D Biol. Crystallogr. 63 833-43 (2007)
PMID: 17582174

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Thioredoxin reductase Chains: A, B
Molecule details ›
Chains: A, B
Length: 311 amino acids
Theoretical weight: 33.58 KDa
Source organism: Helicobacter pylori 26695
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P56431 (Residues: 1-311; Coverage: 100%)
Gene names: HP_0825, trxB
Sequence domains:
Structure domains: FAD/NAD(P)-binding domain

Ligands and Environments

Cofactor: Ligand FAD 2 x FAD

Cofactor: Ligand NAP 2 x NAP
No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21
Unit cell:
a: 50.451Å b: 99.455Å c: 64.765Å
α: 90° β: 97.94° γ: 90°
R R work R free
0.168 0.167 0.193
Expression system: Escherichia coli BL21(DE3)