› › Function and Biology

Solution structure of the F153-to-5-flurotryptophan mutant of human cardiac troponin C

Source organism: Homo sapiens
Biochemical function: actin filament binding
Biological process: cardiac muscle contraction
Cellular component: cardiac Troponin complex

Quick links

GO terms

Sequence families

Pfam Protein families (Pfam)
PF13499
Domain description: EF-hand domain pair
Occurring in:
  1. Troponin C, slow skeletal and cardiac muscles
The deposited structure of PDB entry 2jt8 contains 1 copy of Pfam domain PF13499 (EF-hand domain pair) in Troponin C, slow skeletal and cardiac muscles. Showing 1 copy in chain A.

PF13833
Domain description: EF-hand domain pair
Occurring in:
  1. Troponin C, slow skeletal and cardiac muscles
The deposited structure of PDB entry 2jt8 contains 1 copy of Pfam domain PF13833 (EF-hand domain pair) in Troponin C, slow skeletal and cardiac muscles. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002048
Domain description: EF-hand domain
Occurring in:
  1. Troponin C, slow skeletal and cardiac muscles
IPR018247
Domain description: EF-Hand 1, calcium-binding site
Occurring in:
  1. Troponin C, slow skeletal and cardiac muscles
IPR011992
Domain description: EF-hand domain pair
Occurring in:
  1. Troponin C, slow skeletal and cardiac muscles

Structure domain

CATH CATH domain
1.10.238.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Recoverin; domain 1
Homology: EF-hand
Occurring in:
  1. Troponin C, slow skeletal and cardiac muscles
The deposited structure of PDB entry 2jt8 contains 1 copy of CATH domain 1.10.238.10 (Recoverin; domain 1) in Troponin C, slow skeletal and cardiac muscles. Showing 1 copy in chain A.
SCOP SCOP annotation
47502
Class: All alpha proteins
Fold: EF Hand-like
Superfamily: EF-hand
Occurring in:
  1. Troponin C, slow skeletal and cardiac muscles
The deposited structure of PDB entry 2jt8 contains 1 copy of SCOP domain 47502 (Calmodulin-like) in Troponin C, slow skeletal and cardiac muscles. Showing 1 copy in chain A.

Quick links