› › Function and Biology

Crystal structure of human SENP1 mutant (C603S) in complex with SUMO-1

Source organism: Homo sapiens
Biochemical function: cysteine-type peptidase activity
Biological process: proteolysis
Cellular component: not assigned

Quick links

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF11976
Domain description: Ubiquitin-2 like Rad60 SUMO-like
Occurring in:
  1. Small ubiquitin-related modifier 1
The deposited structure of PDB entry 2g4d contains 2 copies of Pfam domain PF11976 (Ubiquitin-2 like Rad60 SUMO-like) in Small ubiquitin-related modifier 1. Showing 1 copy in chain B.

PF02902
Domain description: Ulp1 protease family, C-terminal catalytic domain
Occurring in:
  1. Sentrin-specific protease 1
The deposited structure of PDB entry 2g4d contains 2 copies of Pfam domain PF02902 (Ulp1 protease family, C-terminal catalytic domain) in Sentrin-specific protease 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000626
Domain description: Ubiquitin-like domain
Occurring in:
  1. Small ubiquitin-related modifier 1
IPR003653
Domain description: Ulp1 protease family, C-terminal catalytic domain
Occurring in:
  1. Sentrin-specific protease 1
IPR022617
Domain description: Rad60/SUMO-like domain
Occurring in:
  1. Small ubiquitin-related modifier 1
IPR046332
Domain description: Small ubiquitin-related modifier 1, Ubl domain
Occurring in:
  1. Small ubiquitin-related modifier 1
IPR029071
Domain description: Ubiquitin-like domain superfamily
Occurring in:
  1. Small ubiquitin-related modifier 1
IPR038765
Domain description: Papain-like cysteine peptidase superfamily
Occurring in:
  1. Sentrin-specific protease 1

Structure domains

CATH CATH domains
3.10.20.90
Class: Alpha Beta
Architecture: Roll
Topology: Ubiquitin-like (UB roll)
Homology: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Occurring in:
  1. Small ubiquitin-related modifier 1
The deposited structure of PDB entry 2g4d contains 2 copies of CATH domain 3.10.20.90 (Ubiquitin-like (UB roll)) in Small ubiquitin-related modifier 1. Showing 1 copy in chain B.
3.40.395.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Adenoviral Proteinase; Chain
Homology: Adenoviral Proteinase; Chain A
Occurring in:
  1. Sentrin-specific protease 1
The deposited structure of PDB entry 2g4d contains 2 copies of CATH domain 3.40.395.10 (Adenoviral Proteinase; Chain) in Sentrin-specific protease 1. Showing 1 copy in chain A.
SCOP SCOP annotations
54237
Class: Alpha and beta proteins (a+b)
Fold: beta-Grasp (ubiquitin-like)
Superfamily: Ubiquitin-like
Occurring in:
  1. Small ubiquitin-related modifier 1
The deposited structure of PDB entry 2g4d contains 2 copies of SCOP domain 54237 (Ubiquitin-related) in Small ubiquitin-related modifier 1. Showing 1 copy in chain B.
54054
Class: Alpha and beta proteins (a+b)
Fold: Cysteine proteinases
Superfamily: Cysteine proteinases
Occurring in:
  1. Sentrin-specific protease 1
The deposited structure of PDB entry 2g4d contains 2 copies of SCOP domain 54054 (Adenain-like) in Sentrin-specific protease 1. Showing 1 copy in chain A.

Quick links