› 2a5j

X-ray diffraction
1.5Å resolution

Crystal Structure of Human RAB2B

Released:
DOI: 10.2210/pdb2a5j/pdb
PDB entry 2a5j coloured by chain, front view.
PDB entry 2a5j coloured by chain, side view.
PDB entry 2a5j coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Dong A, Wang J, Shen Y, Arrowsmith CH, Edwards AM, Sundstrom M, Bochkarev A, Park HW, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186712 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras-related protein Rab-2B Chain: A
Molecule details ›
Chain: A
Length: 191 amino acids
Theoretical weight: 21.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q8WUD1 (Residues: 5-176; Coverage: 80%)
Gene name: RAB2B
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand GDP 1 x GDP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P212121
Unit cell:
a: 44.104Å b: 54.732Å c: 70.765Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.195 0.225
Expression system: Escherichia coli BL21

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