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Human DEAD-box RNA helicase DDX10, DEAD domain in complex with ADP

X-ray diffraction
2.15Å resolution
PDB entry 2pl3 coloured by chain, front view.
PDB entry 2pl3 coloured by chain, side view.
PDB entry 2pl3 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Probable ATP-dependent RNA helicase DDX10
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Multimeric state: monomeric
Accessible surface area: 11452.93 Å2
Buried surface area: 1327.51 Å2
Dissociation area: 101.62 Å2
Dissociation energy (ΔGdiss): -1.21 kcal/mol
Dissociation entropy (TΔSdiss): -1.26 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-171602

Macromolecules

Probable ATP-dependent RNA helicase DDX10
Chain: A
Length: 236 amino acids
Theoretical weight: 26.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13206 (Residues: 47-280; Coverage: 27%)
Gene name: DDX10
Pfam: DEAD/DEAH box helicase
InterPro:
CATH: P-loop containing nucleotide triphosphate hydrolases
Probable ATP-dependent RNA helicase DDX10 in PDB entry 2pl3, assembly 1, front view.
Probable ATP-dependent RNA helicase DDX10 in PDB entry 2pl3, assembly 1, side view.
Probable ATP-dependent RNA helicase DDX10 in PDB entry 2pl3, assembly 1, top view.
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