› 1irc

X-ray diffraction
2.17Å resolution

CYSTEINE RICH INTESTINAL PROTEIN

Released:
DOI: 10.2210/pdb1irc/pdb
PDB entry 1irc coloured by chain, front view.
PDB entry 1irc coloured by chain, side view.
PDB entry 1irc coloured by chain, top view.
Source organism: Physeter catodon
Primary publication:
Replacement of the proximal ligand of sperm whale myoglobin with free imidazole in the mutant His-93-->Gly.
Barrick D
Biochemistry 33 6546-54 (1994)
PMID: 8204590

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135409 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myoglobin Chain: A
Molecule details ›
Chain: A
Length: 154 amino acids
Theoretical weight: 17.29 KDa
Source organism: Physeter catodon
Expression system: Escherichia coli
UniProt:
  • Canonical: P02185 (Residues: 1-154; Coverage: 100%)
Gene name: MB
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

2 bound ligands:
Ligand HEM 1 x HEM
Ligand IMD 1 x IMD
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 40.15Å b: 49.04Å c: 79.14Å
α: 90° β: 90° γ: 90°
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Structure and regulation of soluble guanylate cyclase.
Derbyshire et al. (2012)
6 more

2 mentions without citation

The H93G Myoglobin Cavity Mutant as a Versatile Scaffold for Modeling Heme Iron Coordination Structures in Protein Active Sites and Their Characterization with Magnetic Circular Dichroism Spectroscopy.
Du et al. (2011)
1 more