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PYRUVOYL DEPENDENT ASPARTATE DECARBOXYLASE

Source organism: Escherichia coli
Biochemical function: aspartate 1-decarboxylase activity
Biological process: alanine biosynthetic process
Cellular component: not assigned

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EC 4.1.1.11: Aspartate 1-decarboxylase

Reaction catalysed:
L-aspartate = beta-alanine + CO(2)
Systematic name:
L-aspartate 1-carboxy-lyase (beta-alanine-forming)
Alternative Name(s):
  • Aspartate alpha-decarboxylase
  • Aspartic alpha-decarboxylase
  • L-aspartate 1-carboxy-lyase
  • L-aspartate alpha-decarboxylase

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF02261
Domain description: Aspartate decarboxylase
Occurring in:
  1. Aspartate 1-decarboxylase alpha chain
The deposited structure of PDB entry 1aw8 contains 2 copies of Pfam domain PF02261 (Aspartate decarboxylase) in Aspartate 1-decarboxylase alpha chain. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR003190
Domain description: Aspartate decarboxylase
Occurring in:
  1. Aspartate 1-decarboxylase beta chain
  2. Aspartate 1-decarboxylase alpha chain
IPR009010
Domain description: Aspartate decarboxylase-like domain superfamily
Occurring in:
  1. Aspartate 1-decarboxylase beta chain
  2. Aspartate 1-decarboxylase alpha chain

Structure domain

CATH CATH domain
2.40.40.20
Class: Mainly Beta
Architecture: Beta Barrel
Topology: Barwin-like endoglucanases
Homology: Barwin-like endoglucanases
Occurring in:
  1. Aspartate 1-decarboxylase alpha chain
The deposited structure of PDB entry 1aw8 contains 2 copies of CATH domain 2.40.40.20 (Barwin-like endoglucanases) in Aspartate 1-decarboxylase alpha chain. Showing 1 copy in chain B.
SCOP SCOP annotation
50693
Class: All beta proteins
Fold: Double psi beta-barrel
Superfamily: ADC-like
Occurring in:
  1. Aspartate 1-decarboxylase beta chain
  2. Aspartate 1-decarboxylase alpha chain
The deposited structure of PDB entry 1aw8 contains 2 copies of SCOP domain 50693 (Pyruvoyl dependent aspartate decarboxylase, ADC) in Aspartate 1-decarboxylase beta chain. Showing 1 copy in chain A.

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