PDBe 1p7w

X-ray diffraction
1.02Å resolution

Crystal structure of the complex of Proteinase K with a designed heptapeptide inhibitor Pro-Ala-Pro-Phe-Ala-Ser-Ala at atomic resolution

Released:
Entry authors: Bilgrami S, Perbandt M, Chandra V, Banumathi S, Kaur P, Betzel C, Singh TP

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Proteinase K Chain: A
Molecule details ›
Chain: A
Length: 279 amino acids
Theoretical weight: 28.96 KDa
Source organism: Parengyodontium album
UniProt:
  • Best match: P06873 (Residues: 106-384)
Gene name: PROK
inhibitor peptide Chain: B
Molecule details ›
Chain: B
Length: 7 amino acids
Theoretical weight: 660 Da
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P43212
Unit cell:
a: 67.835Å b: 67.835Å c: 101.563Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.129 0.129 0.142
Expression system: Not provided