› 6mjd

Solution NMR

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138691 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mu-conotoxin GIIIC Chain: A
Molecule details ›
Chain: A
Length: 23 amino acids
Theoretical weight: 2.61 KDa
Source organism: Conus geographus
Expression system: Not provided
UniProt:
  • Canonical: P05482 (Residues: 1-22; Coverage: 100%)
Sequence domains: Mu-Conotoxin

Ligands and Environments

No bound ligands
1 modified residue:
Ligand HYP 3 x HYP

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 71%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

1 review citation

Historical Perspective of the Characterization of Conotoxins Targeting Voltage-Gated Sodium Channels.
Groome JR. (2023)
2 other articles

1 mention without citation

NMR Structure of μ-Conotoxin GIIIC: Leucine 18 Induces Local Repacking of the N-Terminus Resulting in Reduced NaV Channel Potency.
Harvey et al. (2018)