› 5djo

X-ray diffraction
1.74Å resolution

Crystal structure of the CC1-FHA tandem of Kinesin-3 KIF13A

Released:
DOI: 10.2210/pdb5djo/pdb
PDB entry 5djo coloured by chain, front view.
PDB entry 5djo coloured by chain, side view.
PDB entry 5djo coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural Correlation of the Neck Coil with the Coiled-coil (CC1)-Forkhead-associated (FHA) Tandem for Active Kinesin-3 KIF13A.
Ren J, Huo L, Wang W, Zhang Y, Li W, Lou J, Xu T, Feng W
J Biol Chem 291 3581-94 (2016)
PMID: 26680000

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190164 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinesin-like protein KIF13A Chains: A, B
Molecule details ›
Chains: A, B
Length: 174 amino acids
Theoretical weight: 19.81 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9EQW7 (Residues: 386-555; Coverage: 10%)
Gene name: Kif13a
Sequence domains:
Structure domains: Tumour Suppressor Smad4

Ligands and Environments

3 bound ligands:
Ligand FMT 5 x FMT
Ligand ACY 1 x ACY
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2
Unit cell:
a: 99.154Å b: 50.014Å c: 66.941Å
α: 90° β: 91.97° γ: 90°
R-values:
R R work R free
0.166 0.163 0.221
Expression system: Escherichia coli

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Citations

2 review citations

Intracellular Cargo Transport by Kinesin-3 Motors.
Siddiqui et al. (2017)
1 more

1 mention without citation

Structural Correlation of the Neck Coil with the Coiled-coil (CC1)-Forkhead-associated (FHA) Tandem for Active Kinesin-3 KIF13A.
Ren et al. (2016)