› 5b86

X-ray diffraction
3.02Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178881 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor necrosis factor alpha-induced protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 600 amino acids
Theoretical weight: 68.57 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q61333 (Residues: 94-691; Coverage: 87%)
Gene name: Tnfaip2
Sequence domains: Exocyst complex component Sec6

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 18 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P212121
Unit cell:
a: 91.41Å b: 107.829Å c: 229.58Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.232 0.229 0.292
Expression system: Escherichia coli

Quick links

Citations

17 review citations

Extracellular Vesicles, Tunneling Nanotubes, and Cellular Interplay: Synergies and Missing Links.
Nawaz et al. (2017)
16 more

3 mentions without citation

Distinct Roles for the N- and C-terminal Regions of M-Sec in Plasma Membrane Deformation during Tunneling Nanotube Formation.
Kimura et al. (2016)
2 more