› 4rml

X-ray diffraction
1.6Å resolution

Crystal structure of the Olfactomedin domain of latrophilin 3 in C2221 crystal form

Released:
DOI: 10.2210/pdb4rml/pdb
PDB entry 4rml coloured by chain, front view.
PDB entry 4rml coloured by chain, side view.
PDB entry 4rml coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development.
Ranaivoson FM, Liu Q, Martini F, Bergami F, von Daake S, Li S, Lee D, Demeler B, Hendrickson WA, Comoletti D
Structure 23 1665-1677 (2015)
PMID: 26235031

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182364 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adhesion G protein-coupled receptor L3 Chain: A
Molecule details ›
Chain: A
Length: 321 amino acids
Theoretical weight: 36.63 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q80TS3 (Residues: 199-495; Coverage: 20%)
Gene names: Adgrl3, Kiaa0768, Lec3, Lphn3
Sequence domains: Olfactomedin-like domain

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand TRS 1 x TRS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: C2221
Unit cell:
a: 78.806Å b: 96.819Å c: 79.203Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.177 0.176 0.196
Expression system: Homo sapiens

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Citations

8 review citations

Adhesion G protein-coupled receptors in nervous system development and disease.
Langenhan et al. (2016)
7 more

3 mentions without citation

Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development.
Ranaivoson et al. (2015)
2 more