› 3f4r

X-ray diffraction
1.6Å resolution

Crystal structure of Wolbachia pipientis alpha-DsbA1

Released:
DOI: 10.2210/pdb3f4r/pdb
PDB entry 3f4r coloured by chain, front view.
PDB entry 3f4r coloured by chain, side view.
PDB entry 3f4r coloured by chain, top view.
Source organism: Wolbachia endosymbiont of Drosophila melanogaster
Primary publication:
Structural and functional characterization of the oxidoreductase alpha-DsbA1 from Wolbachia pipientis.
Kurz M, Iturbe-Ormaetxe I, Jarrott R, Shouldice SR, Wouters MA, Frei P, Glockshuber R, O'Neill SL, Heras B, Martin JL
Antioxid Redox Signal 11 1485-500 (2009)
PMID: 19265485

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180959 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin-like fold domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 226 amino acids
Theoretical weight: 26.56 KDa
Source organism: Wolbachia endosymbiont of Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: Q73GA4 (Residues: 19-234; Coverage: 92%)
Gene name: WD_1055
Sequence domains: Thioredoxin
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand PGE 1 x PGE
Ligand 1PE 1 x 1PE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: C2
Unit cell:
a: 71.4Å b: 49.6Å c: 69.7Å
α: 90° β: 107° γ: 90°
R-values:
R R work R free
0.168 0.165 0.192
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Structure and function of DsbA, a key bacterial oxidative folding catalyst.
Shouldice et al. (2011)
5 more

7 mentions without citation

Structural bioinformatic analysis of DsbA proteins and their pathogenicity associated substrates.
Santos-Martin et al. (2021)
6 more