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Crystal Structure of Human Osteoclast Stimulating Factor

Source organism: Homo sapiens
Biochemical function: SH3 domain binding
Biological process: signal transduction
Cellular component: ficolin-1-rich granule lumen

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF12796
Domain description: Ankyrin repeats (3 copies)
Occurring in:
  1. Osteoclast-stimulating factor 1
The deposited structure of PDB entry 3ehq contains 4 copies of Pfam domain PF12796 (Ankyrin repeats (3 copies)) in Osteoclast-stimulating factor 1. Showing 2 copies in chain A.

PF00018
Domain description: SH3 domain
Occurring in:
  1. Osteoclast-stimulating factor 1
The deposited structure of PDB entry 3ehq contains 2 copies of Pfam domain PF00018 (SH3 domain) in Osteoclast-stimulating factor 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002110
Domain description: Ankyrin repeat
Occurring in:
  1. Osteoclast-stimulating factor 1
IPR001452
Domain description: SH3 domain
Occurring in:
  1. Osteoclast-stimulating factor 1
IPR036770
Domain description: Ankyrin repeat-containing domain superfamily
Occurring in:
  1. Osteoclast-stimulating factor 1
IPR036028
Domain description: SH3-like domain superfamily
Occurring in:
  1. Osteoclast-stimulating factor 1

Structure domains

CATH CATH domains
1.25.40.20
Class: Mainly Alpha
Architecture: Alpha Horseshoe
Topology: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Homology: Ankyrin repeat-containing domain
Occurring in:
  1. Osteoclast-stimulating factor 1
The deposited structure of PDB entry 3ehq contains 2 copies of CATH domain 1.25.40.20 (Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat) in Osteoclast-stimulating factor 1. Showing 1 copy in chain A.
2.30.30.40
Class: Mainly Beta
Architecture: Roll
Topology: SH3 type barrels.
Homology: SH3 Domains
Occurring in:
  1. Osteoclast-stimulating factor 1
The deposited structure of PDB entry 3ehq contains 2 copies of CATH domain 2.30.30.40 (SH3 type barrels.) in Osteoclast-stimulating factor 1. Showing 1 copy in chain A.

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