› 2rjd

X-ray diffraction
1.65Å resolution

Crystal structure of L3MBTL1 protein

Released:
DOI: 10.2210/pdb2rjd/pdb
PDB entry 2rjd coloured by chain, front view.
PDB entry 2rjd coloured by chain, side view.
PDB entry 2rjd coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
L3MBTL1 recognition of mono- and dimethylated histones.
Min J, Allali-Hassani A, Nady N, Qi C, Ouyang H, Liu Y, MacKenzie F, Vedadi M, Arrowsmith CH
Nat Struct Mol Biol 14 1229-30 (2007)
PMID: 18026117

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-195224 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lethal(3)malignant brain tumor-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 331 amino acids
Theoretical weight: 37.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y468 (Residues: 268-598; Coverage: 39%)
Gene names: KIAA0681, L3MBT, L3MBTL, L3MBTL1
Sequence domains: mbt repeat
Structure domains: SH3 type barrels.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ DW
Spacegroup: P21212
Unit cell:
a: 85.518Å b: 94.195Å c: 59.009Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.202 0.23
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

57 review citations

Double-strand break repair: 53BP1 comes into focus.
Panier et al. (2014)
56 more