› › Structure analysis

THE X-RAY STRUCTURE OF A COMPLEX OF SIALIC ACID AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE

X-ray diffraction
2Å resolution
PDB entry 2qwb coloured by chain, front view.
PDB entry 2qwb coloured by chain, side view.
PDB entry 2qwb coloured by chain, top view.
Source organism: Influenza A virus
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Neuraminidase
hide full assembly name
Multimeric state: homo tetramer
Accessible surface area: 46295.23 Å2
Buried surface area: 29822.28 Å2
Dissociation area: 25.31 Å2
Dissociation energy (ΔGdiss): 3.69 kcal/mol
Dissociation entropy (TΔSdiss): 0.04 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-137058

Macromolecules

Neuraminidase
Chain: A
Length: 388 amino acids
Theoretical weight: 43.7 KDa
Source organism: Influenza A virus
UniProt:
  • Canonical: P03472 (Residues: 83-470; Coverage: 83%)
Gene name: NA
Pfam: Neuraminidase
InterPro:
CATH: Neuraminidase
SCOP: Sialidases (neuraminidases)
Neuraminidase in PDB entry 2qwb, assembly 1, front view.
Neuraminidase in PDB entry 2qwb, assembly 1, side view.
Neuraminidase in PDB entry 2qwb, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links