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Solution NMR

Structure of helix 69 from escherichia coli 23s ribosomal rna

Released:
DOI: 10.2210/pdb2mer/pdb
PDB entry 2mer coloured by chain, ensemble of 10 models, front view.
PDB entry 2mer coloured by chain, ensemble of 10 models, side view.
PDB entry 2mer coloured by chain, ensemble of 10 models, top view.
Source organism: Synthetic construct
Primary publication:
Structure modulation of helix 69 from Escherichia coli 23S ribosomal RNA by pseudouridylations.
Jiang J, Aduri R, Chow CS, SantaLucia J
Nucleic Acids Res 42 3971-81 (2014)
PMID: 24371282

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196497 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA_(5'-R(P*GP*GP*CP*CP*GP*(PSU)P*AP*AP*CP*(PSU)P*AP*(PSU)P*AP*AP*CP*GP*GP*UP*C)-3') Chain: A
Molecule details ›
Chain: A
Length: 19 nucleotides
Theoretical weight: 6.08 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand PSU 3 x PSU

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 57%
Refinement method: simulated annealing, molecular dynamics, torsion angle dynamics
Expression system: Not provided

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Citations

4 review citations

Pseudouridine: still mysterious, but never a fake (uridine)!
Spenkuch et al. (2014)
3 more

12 mentions without citation

Advances in oligonucleotide drug delivery.
Roberts et al. (2020)
11 more