2m0s

Solution NMR

Solution Structure of the trans-membrane domain of the NS2A of dengue virus

Released:
Source organism: Dengue virus 2
Primary publication:
Membrane topology and function of dengue virus NS2A protein.
J Virol 87 4609-22 (2013)
PMID: 23408612

Function and Biology Details

Reactions catalysed:
Selective hydrolysis of -Xaa-Xaa-|-Yaa- bonds in which each of the Xaa can be either Arg or Lys and Yaa can be either Ser or Ala.
NTP + H(2)O = NDP + phosphate
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195514 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NS2A protein Chain: A
Molecule details ›
Chain: A
Length: 28 amino acids
Theoretical weight: 2.98 KDa
Source organism: Dengue virus 2
Expression system: Not provided
UniProt:
  • Canonical: Q9YKL3 (Residues: 1194-1221; Coverage: 1%)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 60%
Refinement method: torsion angle dynamics
Expression system: Not provided