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Structure of casein kinase gamma 3 in complex with inhibitor

X-ray diffraction
1.85Å resolution
PDB entry 2izu coloured by chain, front view.
PDB entry 2izu coloured by chain, side view.
PDB entry 2izu coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Casein kinase I isoform gamma-3
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Multimeric state: monomeric
Accessible surface area: 13476.21 Å2
Buried surface area: 1175.0 Å2
Dissociation area: 75.82 Å2
Dissociation energy (ΔGdiss): -1 kcal/mol
Dissociation entropy (TΔSdiss): -0.38 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-195374

Macromolecules

Casein kinase I isoform gamma-3
Chain: A
Length: 330 amino acids
Theoretical weight: 38.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y6M4 (Residues: 33-362; Coverage: 74%)
  • Best match: Q9Y6M4-5 (Residues: 1-287)
Gene name: CSNK1G3
Pfam:
InterPro:
CATH:
Casein kinase I isoform gamma-3 in PDB entry 2izu, assembly 1, front view.
Casein kinase I isoform gamma-3 in PDB entry 2izu, assembly 1, side view.
Casein kinase I isoform gamma-3 in PDB entry 2izu, assembly 1, top view.
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