› 2cc6

X-ray diffraction
1.27Å resolution

Complexes of Dodecin with Flavin and Flavin-like Ligands

Released:
DOI: 10.2210/pdb2cc6/pdb
PDB entry 2cc6 coloured by chain, front view.
PDB entry 2cc6 coloured by chain, side view.
PDB entry 2cc6 coloured by chain, top view.
Source organism: Halobacterium salinarum R1
Primary publication:
Dodecins: a family of lumichrome binding proteins.
Grininger M, Zeth K, Oesterhelt D
J Mol Biol 357 842-57 (2006)
PMID: 16460756

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109191 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dodecin Chain: A
Molecule details ›
Chain: A
Length: 68 amino acids
Theoretical weight: 7.44 KDa
Source organism: Halobacterium salinarum R1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: B0R5M0 (Residues: 1-68; Coverage: 100%)
Gene name: OE_3073R
Sequence domains: Dodecin
Structure domains: Flavin-binding protein dodecin

Ligands and Environments

5 bound ligands:
Ligand MG 2 x MG
Ligand NA 1 x NA
Ligand CL 1 x CL
Ligand SO4 1 x SO4
Ligand LUM 1 x LUM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: F4132
Unit cell:
a: 141.72Å b: 141.72Å c: 141.72Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.207 0.232
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Metabolite damage and its repair or pre-emption.
Linster et al. (2013)
3 more

6 mentions without citation

Structural adaptation of extreme halophilic proteins through decrease of conserved hydrophobic contact surface.
Siglioccolo et al. (2011)
5 more