Crystal Structure of the human PXR-LBD in complex with an SRC-1 coactivator peptide and SR12813
The structure was published by Watkins, R.E., Davis-Searles, P.R., Lambert, M.H., and Redinbo, M.R., in 2003 in a paper entitled "Coactivator binding promotes the specific interaction between ligand and the pregnane X receptor" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2003.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Orphan nuclear receptor PXR and Nuclear Receptor Coactivator 1 isoform 3.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: