1cz0 Summary

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INTRON ENCODED HOMING ENDONUCLEASE I-PPOI/DNA COMPLEX LACKING CATALYTIC METAL ION

The structure was published by Galburt, E.A., Chevalier, B., Tang, W., et al., Flick, K.E., Monnat Jr., R.J., and Stoddard, B.L., in 1999 in a paper entitled "A novel endonuclease mechanism directly visualized for I-PpoI." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 1999.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3') and INTRON-ENCODED HOMING ENDONUCLEASE I-PPOI.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A INTRON-ENCODED HOMING ENDONUCLEASE I-PPOI Q94702 (2-163) (PPO1_PHYPO)search Physarum polycephalumsearch 99% 162 100%
B INTRON-ENCODED HOMING ENDONUCLEASE I-PPOI Q94702 (2-163) (PPO1_PHYPO)search Physarum polycephalumsearch 99% 162 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q94702 (2 - 163) INTRON-ENCODED HOMING ENDONUCLEASE I-PPOI Physarum polycephalum

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (Q94702) Intron-encoded homing endonucleasessearch Homing Intron 3 (I-ppo) Encoded Endonuclease; Chain Asearch PF05551: Zinc-binding loop region of homing endonucleasesearch

Chain ID Molecular function (GO) Biological process (GO)
A, B (Q94702) endonuclease activitysearch hydrolase activitysearch nuclease activitysearch nucleic acid phosphodiester bond hydrolysissearch intron homingsearch

Chain InterPro annotation
A, B Zinc-binding loop region of homing endonucleasesearch