1cqt Summary

pdbe.org/1cqt
spacer

CRYSTAL STRUCTURE OF A TERNARY COMPLEX CONTAINING AN OCA-B PEPTIDE, THE OCT-1 POU DOMAIN, AND AN OCTAMER ELEMENT

The structure was published by Chasman, D., Cepek, K., Sharp, P.A., and Pabo, C.O., in 1999 in a paper entitled "Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.2 Å and deposited in 1999.

The experimental data on which the structure is based was not deposited.

This entry contains 8 copies of 4 unique biopolymers (complete list).

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 1 P14859 (278-438) (PO2F1_HUMAN)search Homo sapienssearch < 90% 163 82%
B POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 1 P14859 (278-439) (PO2F1_HUMAN)search Homo sapienssearch < 90% 163 82%
I POU DOMAIN, CLASS 2, ASSOCIATING FACTOR 1 Q16633 (1-44) (OBF1_HUMAN)search Homo sapienssearch < 90% 44 52%
J POU DOMAIN, CLASS 2, ASSOCIATING FACTOR 1 Q16633 (1-44) (OBF1_HUMAN)search Homo sapienssearch < 90% 44 52%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P14859 (278 - 438) POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 1 Homo sapiens
Q16633 (1 - 44) POU DOMAIN, CLASS 2, ASSOCIATING FACTOR 1 Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B Homeodomainsearch, POU-specific domainsearch lambda repressor-like DNA-binding domainssearch, Homeodomain-likesearch Homeobox domainsearch, Pou domain - N-terminal to homeobox domainsearch
I, J POU domain, class 2, associating factor 1search

Chain ID Molecular function (GO) Biological process (GO)
A, B (P14859) sequence-specific DNA binding transcription factor activitysearch sequence-specific DNA bindingsearch DNA bindingsearch regulation of transcription, DNA-templatedsearch

Chain InterPro annotation
A, B POU-specificsearch Homeobox domainsearch Homeodomain-likesearch Lambda repressor-like, DNA-binding domainsearch POU domainsearch Homeobox, conserved sitesearch
I, J POU, class 2, associating factor 1search